Difference between revisions of "TcyM"
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= [[Categories]] containing this gene/protein = | = [[Categories]] containing this gene/protein = | ||
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= This gene is a member of the following [[regulons]] = | = This gene is a member of the following [[regulons]] = | ||
{{SubtiWiki regulon|[[CymR regulon]]}}, | {{SubtiWiki regulon|[[CymR regulon]]}}, | ||
| − | {{SubtiWiki regulon|[[ | + | {{SubtiWiki regulon|[[AscR regulon]]}} |
=The gene= | =The gene= | ||
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=Expression and regulation= | =Expression and regulation= | ||
| − | * '''Operon:''' ''[[ | + | * '''Operon:''' ''[[snaA]]-[[tcyJ]]-[[tcyK]]-[[tcyL]]-[[tcyM]]-[[tcyN]]-[[cmoO]]-[[cmoI]]-[[cmoJ]]-[[ribR]]-[[sndA]]-[[ytnM]]'' {{PubMed|15668000}} |
* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=tcyM_3005122_3005829_-1 tcyM] {{PubMed|22383849}} | * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=tcyM_3005122_3005829_-1 tcyM] {{PubMed|22383849}} | ||
| − | * '''Sigma factor:''' [[SigA]] {{PubMed|15272571}} | + | * '''[[Sigma factor]]:''' [[SigA]] {{PubMed|15272571}} |
* '''Regulation:''' | * '''Regulation:''' | ||
** repressed in the presence of cysteine ([[CymR]]) {{PubMed|16109943}} | ** repressed in the presence of cysteine ([[CymR]]) {{PubMed|16109943}} | ||
| + | ** induced in the presence of S-methyl-cysteine ([[AscR]]) {{PubMed|23944997}} | ||
* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
** [[CymR]]: transcription repression {{PubMed|16109943}} | ** [[CymR]]: transcription repression {{PubMed|16109943}} | ||
| − | ** [[ | + | ** [[AscR]]: transcription activation {{PubMed|16109943}} |
* '''Additional information:''' | * '''Additional information:''' | ||
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=References= | =References= | ||
| − | + | <pubmed>15262924,10092453,16109943,12193636,15668000 15272571 23944997</pubmed> | |
| − | <pubmed>15262924,10092453,16109943,12193636,15668000 </pubmed> | ||
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[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 10:23, 18 August 2013
- Description: cystine ABC transporter (permease)
| Gene name | tcyM |
| Synonyms | ytmM |
| Essential | no |
| Product | cystine ABC transporter (permease) |
| Function | cystine uptake |
| Gene expression levels in SubtiExpress: tcyM | |
| Interactions involving this protein in SubtInteract: TcyM | |
| Metabolic function and regulation of this protein in SubtiPathways: Riboflavin / FAD | |
| MW, pI | 25 kDa, 8.767 |
| Gene length, protein length | 705 bp, 235 aa |
| Immediate neighbours | tcyN, tcyL |
| Sequences | Protein DNA DNA_with_flanks |
Genetic context 
This image was kindly provided by SubtiList
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Expression at a glance PubMed
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Contents
Categories containing this gene/protein
ABC transporters, biosynthesis/ acquisition of amino acids, membrane proteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU29350
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: binding-protein-dependent transport system permease family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization:
- cell membrane PubMed
Database entries
- Structure:
- UniProt: O34931
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Regulation:
- Additional information:
Biological materials
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
