Difference between revisions of "FtsE"

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* '''Description:''' [[ABC transporter]] (ATP-binding protein) ([[FtsE]]-[[FtsX]]), required for proper activation of [[Spo0A]] and initiation of sporulation <br/><br/>
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* '''Description:''' [[ABC transporter]] (ATP-binding protein) ([[FtsE]]-[[FtsX]]), required for [[CwlO]] activity and for proper activation of [[Spo0A]] and initiation of [[sporulation]] <br/><br/>
  
 
{| align="right" border="1" cellpadding="2"  
 
{| align="right" border="1" cellpadding="2"  
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|style="background:#ABCDEF;" align="center"| '''Product''' || [[ABC transporter]] (ATP-binding protein)  
 
|style="background:#ABCDEF;" align="center"| '''Product''' || [[ABC transporter]] (ATP-binding protein)  
 
|-
 
|-
|style="background:#ABCDEF;" align="center"|'''Function''' || initiation of sporulation
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|style="background:#ABCDEF;" align="center"|'''Function''' || control of [[cell wall synthesis]]
 
|-
 
|-
 
|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU35260 ftsE]
 
|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU35260 ftsE]
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= [[Categories]] containing this gene/protein =
 
= [[Categories]] containing this gene/protein =
 
{{SubtiWiki category|[[ABC transporters]]}},
 
{{SubtiWiki category|[[ABC transporters]]}},
 +
{{SubtiWiki category|[[cell wall synthesis]]}},
 
{{SubtiWiki category|[[phosphorelay]]}},
 
{{SubtiWiki category|[[phosphorelay]]}},
 
{{SubtiWiki category|[[membrane proteins]]}}
 
{{SubtiWiki category|[[membrane proteins]]}}
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===Phenotypes of a mutant ===
 
===Phenotypes of a mutant ===
 +
* a ''[[ftsE]]'' mutation is synthetically lethal with a ''[[lytE]]'' mutation (due to a lack of autolysin activity) {{PubMed|xxx}}
 +
* shorter, fatter cells {{PubMed|xxx}}
  
 
=== Database entries ===
 
=== Database entries ===
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* '''Catalyzed reaction/ biological activity:'''  
 
* '''Catalyzed reaction/ biological activity:'''  
 +
** necessary for the autolysin activity of [[CwlO]] {{PubMed|xxx}}
  
 
* '''Protein family:'''
 
* '''Protein family:'''
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* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=ftsE_3624821_3625507_-1 ftsE] {{PubMed|22383849}}
 
* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=ftsE_3624821_3625507_-1 ftsE] {{PubMed|22383849}}
  
* '''Sigma factor:'''  
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* '''[[Sigma factor]]:'''  
  
 
* '''Regulation:'''  
 
* '''Regulation:'''  

Revision as of 12:04, 16 July 2013

Gene name ftsE
Synonyms
Essential no
Product ABC transporter (ATP-binding protein)
Function control of cell wall synthesis
Gene expression levels in SubtiExpress: ftsE
Interactions involving this protein in SubtInteract: FtsE
MW, pI 25 kDa, 8.419
Gene length, protein length 684 bp, 228 aa
Immediate neighbours ftsX, cccB
Sequences Protein DNA DNA_with_flanks
Genetic context
FtsE context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
FtsE expression.png















Categories containing this gene/protein

ABC transporters, cell wall synthesis, phosphorelay, membrane proteins

This gene is a member of the following regulons

Spo0A regulon

The gene

Basic information

  • Locus tag: BSU35260

Phenotypes of a mutant

  • a ftsE mutation is synthetically lethal with a lytE mutation (due to a lack of autolysin activity) PubMed
  • shorter, fatter cells PubMed

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
    • necessary for the autolysin activity of CwlO PubMed
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • repressed under conditions that trigger sporulation (Spo0A) PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References