Difference between revisions of "UreC"

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Revision as of 14:47, 16 May 2013

  • Description: urease (alpha subunit)

Gene name ureC
Synonyms
Essential no
Product urease (alpha subunit)
Function utilization of urea as alternative nitrogen source
Gene expression levels in SubtiExpress: ureC
Interactions involving this protein in SubtInteract: UreC
Metabolic function and regulation of this protein in SubtiPathways:
Purine catabolism, Ammonium/ glutamate, Alternative nitrogen sources
MW, pI 61 kDa, 5.091
Gene length, protein length 1707 bp, 569 aa
Immediate neighbours ywnA, ureB
Sequences Protein DNA DNA_with_flanks
Genetic context
UreC context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
UreC expression.png




























Categories containing this gene/protein

utilization of nitrogen sources other than amino acids

This gene is a member of the following regulons

CodY regulon, GlnR regulon, PucR regulon, SigH regulon, TnrA regulon

The gene

Basic information

  • Locus tag: BSU36640

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: Urea + H2O = CO2 + 2 NH3 (according to Swiss-Prot)
  • Protein family: urease family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]

Additional information

Expression and regulation

  • Regulation:
    • induced by nitrogen limitation (GlnR, TnrA) PubMed
    • induced in the presence of purine nucleotides (inducer: allantoin) (PucR) PubMed
    • repressed during growth in the presence of branched chain amino acids (CodY) PubMed
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References