Difference between revisions of "CatR"
| Line 27: | Line 27: | ||
<div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div> | <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div> | ||
|- | |- | ||
| − | |colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=yvaP_3457615_3457941_1 Expression at a glance]'''   {{PubMed|22383849}}<br/>[[Image:catR_expression.png|500px]] | + | |colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=yvaP_3457615_3457941_1 Expression at a glance]'''   {{PubMed|22383849}}<br/>[[Image:catR_expression.png|500px|link=http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU33680]] |
|- | |- | ||
|} | |} | ||
Revision as of 14:35, 16 May 2013
- Description: MarR/DUF24 family transcription repressor of the catD-catE operon
| Gene name | catR |
| Synonyms | yvaP |
| Essential | no |
| Product | MarR/DUF24 family transcription repressor |
| Function | resistance against oxidative and electrophile stress |
| Gene expression levels in SubtiExpress: catR | |
| MW, pI | 26 kDa, 9.887 |
| Gene length, protein length | 708 bp, 236 aa |
| Immediate neighbours | yvaO, yvaQ |
| Sequences | Protein DNA DNA_with_flanks |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
transcription factors and their control, resistance against oxidative and electrophile stress
This gene is a member of the following regulons
The CatR regulon:
The gene
Basic information
- Locus tag: BSU33680
Phenotypes of a mutant
increased resistance to catechol and quinones PubMed
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: MarR/DUF24 family transcription repressor of the catD-catE operon PubMed
- Protein family: MarR/DUF24 family
- Paralogous protein(s): YodB
Extended information on the protein
- Kinetic information:
- Domains:
- Modification: in responsse to the presence of diamides or quinones, Cys-7 forms intermolecular disulfide bonds, this results in loss of DNA-bindig ability (induction of catD-catE) PubMed
- Cofactor(s):
- Effectors of protein activity:
Database entries
- Structure:
- UniProt: O32238
- KEGG entry: [2]
- E.C. number:
Additional information
Expression and regulation
- Operon:
- Sigma factor:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Haike Antelmann,University of Greifswald, Germany
Your additional remarks
References
Reviews
Antelmann H, Helmann JD. Thiol-based redox switches and gene regulation. Antioxid Redox Signal. 2011,14:1049-63. PubMed
Haike Antelmann, Michael Hecker, Peter Zuber
Proteomic signatures uncover thiol-specific electrophile resistance mechanisms in Bacillus subtilis.
Expert Rev Proteomics: 2008, 5(1);77-90
[PubMed:18282125]
[WorldCat.org]
[DOI]
(I p)
Original Articles
