Difference between revisions of "FhuC"

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Revision as of 14:32, 16 May 2013

  • Description: hydroxamate siderophore ABC transporter (ATP-binding protein) (ferrichrome und ferrioxamine)

Gene name fhuC
Synonyms
Essential no
Product hydroxamate siderophore ABC transporter
(ATP-binding protein) (ferrichrome und ferrioxamine)
Function siderophore uptake
Gene expression levels in SubtiExpress: fhuC
Interactions involving this protein in SubtInteract: FhuC
Metabolic function and regulation of this protein in SubtiPathways:
metal ion homeostasis
MW, pI 29 kDa, 6.499
Gene length, protein length 807 bp, 269 aa
Immediate neighbours yvrP, fhuG
Sequences Protein DNA DNA_with_flanks
Genetic context
FhuC context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
FhuC expression.png
























Categories containing this gene/protein

ABC transporters, acquisition of iron, iron metabolism, membrane proteins

This gene is a member of the following regulons

Fur regulon

The gene

Basic information

  • Locus tag: BSU33290

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: ATP + H2O + iron chelate(Out) = ADP + phosphate + iron chelate(In) (according to Swiss-Prot)
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [2]

Additional information

Expression and regulation

  • Operon:
  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Juliane Ollinger, Kyung-Bok Song, Haike Antelmann, Michael Hecker, John D Helmann
Role of the Fur regulon in iron transport in Bacillus subtilis.
J Bacteriol: 2006, 188(10);3664-73
[PubMed:16672620] [WorldCat.org] [DOI] (P p)

Noel Baichoo, Tao Wang, Rick Ye, John D Helmann
Global analysis of the Bacillus subtilis Fur regulon and the iron starvation stimulon.
Mol Microbiol: 2002, 45(6);1613-29
[PubMed:12354229] [WorldCat.org] [DOI] (P p)

Y Quentin, G Fichant, F Denizot
Inventory, assembly and analysis of Bacillus subtilis ABC transport systems.
J Mol Biol: 1999, 287(3);467-84
[PubMed:10092453] [WorldCat.org] [DOI] (P p)