Difference between revisions of "SknR"

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Revision as of 14:01, 16 May 2013

Gene name sknR
Synonyms yqaE
Essential yes PubMed
Product transcription repressor
Function control of prophage gene expression
Gene expression levels in SubtiExpress: sknR
MW, pI 13 kDa, 5.42
Gene length, protein length 348 bp, 116 aa
Immediate neighbours yqaF, yqaD
Sequences Protein DNA DNA_with_flanks
Genetic context
YqaE context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
SknR expression.png















Categories containing this gene/protein

transcription factors and their control, Skin element, essential genes

This gene is a member of the following regulons

The SknR regulon: yqaF-yqdA-yqaG-yqaH-yqaI-yqaJ-yqaK-yqaL-yqaM-yqzO-yqaN

The gene

Basic information

  • Locus tag: BSU26350

Phenotypes of a mutant

  • essential in the wild type background (due to overexpression of the toxic proteins YqaH and YqaM) PubMed
  • no phenotype if deleted with the complete skin element PubMed

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Protein family:

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Tatsu Kimura, Yukie Amaya, Kazuo Kobayashi, Naotake Ogasawara, Tsutomu Sato
Repression of sigK intervening (skin) element gene expression by the CI-like protein SknR and effect of SknR depletion on growth of Bacillus subtilis cells.
J Bacteriol: 2010, 192(23);6209-16
[PubMed:20889742] [WorldCat.org] [DOI] (I p)