RluB

• Description: pseudouridine synthase
  
  

Gene name	rluB
Synonyms	ypuL
Essential	no
Product	pseudouridine synthase
Function	23S rRNA modification
Gene expression levels in SubtiExpress: rluB
MW, pI	25 kDa, 10.253
Gene length, protein length	687 bp, 229 aa
Immediate neighbours	resA, spmB
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed 500px

Categories containing this gene/protein

translation, membrane proteins

The gene

Basic information

• Locus tag: BSU23160

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: rRNA uridine = rRNA pseudouridine (according to Swiss-Prot)

• Protein family: pseudouridine synthase rsuA family (according to Swiss-Prot)

• Paralogous protein(s): YtzF

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:
  • cell membrane (according to Swiss-Prot)

Database entries

• Structure:

• UniProt: P35159

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon:

• Expression browser: rluB PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

L Niu, B G Lane, J Ofengand
Cloning and characterization of the 23S RNA pseudouridine 2633 synthase from Bacillus subtilis.
Biochemistry: 1999, 38(2);629-35
[PubMed:9888802] [WorldCat.org] [DOI] (P p)