Difference between revisions of "CapB"

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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[capC]]'', ''[[rbsR]]''
 
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[capC]]'', ''[[rbsR]]''
 
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU35900 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU35900 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU35900 Advanced_DNA]
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU35900 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU35900 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU35900 DNA_with_flanks]
 
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Revision as of 11:26, 14 May 2013

  • Description: capsular polyglutamate biosynthesis

Gene name capB
Synonyms ywsC, pgsB
Essential no
Product poly-gamma-glutamate synthetase
Function capsule synthesis
Gene expression levels in SubtiExpress: capB
MW, pI 43 kDa, 5.073
Gene length, protein length 1179 bp, 393 aa
Immediate neighbours capC, rbsR
Sequences Protein DNA DNA_with_flanks
Genetic context
YwsC context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
CapB expression.png


























Categories containing this gene/protein

capsule biosynthesis and degradation

This gene is a member of the following regulons

DegU regulon

The gene

Basic information

  • Locus tag: BSU35900

Phenotypes of a mutant

no synthesis of the poly-gamma-glutamate capsule PubMed

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: synthesis of poly-gamma-glutamate from L-Glu PubMed
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
  • Regulatory mechanism: DegU-P: transcription activation PubMed
  • Additional information: The operon is not expressed in the lab strain 168 due to lack of expression of DegQ resulting in inactivity of DegS and DegU PubMed

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Reviews

Original publications

Additional publications: PubMed