Difference between revisions of "FrlM"

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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[frlD]]'', ''[[frlN]]''
 
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[frlD]]'', ''[[frlN]]''
 
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU32580 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU32580 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU32580 Advanced_DNA]
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU32580 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU32580 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU32580 DNA_with_flanks]
 
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|colspan="2" | '''Genetic context''' <br/> [[Image:yurM_context.gif]]
 
|colspan="2" | '''Genetic context''' <br/> [[Image:yurM_context.gif]]

Revision as of 11:12, 14 May 2013

Gene name frlM
Synonyms yurM
Essential no
Product aminosugar ABC transporter (permease)
Function uptake of sugar amines
Gene expression levels in SubtiExpress: frlM
Interactions involving this protein in SubtInteract: FrlM
Metabolic function and regulation of this protein in SubtiPathways:
Alternative nitrogen sources
MW, pI 34 kDa, 7.114
Gene length, protein length 900 bp, 300 aa
Immediate neighbours frlD, frlN
Sequences Protein DNA DNA_with_flanks
Genetic context
YurM context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
FrlM expression.png















Categories containing this gene/protein

ABC transporters, utilization of specific carbon sources, utilization of nitrogen sources other than amino acids, membrane proteins

This gene is a member of the following regulons

CodY regulon, FrlR regulon

The gene

Basic information

  • Locus tag: BSU32580

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: MalFG subfamily (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Sigma factor:
  • Regulation:
    • frlB: repressed during growth in the presence of branched chain amino acids (CodY) PubMed
    • frlB: induced in the presence of fructosamine (FrlR) PubMed

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Lehnik-Habrink M, Schaffer M, Mäder U, Diethmaier C, Herzberg C, Stülke J  
RNA processing in Bacillus subtilis: identification of targets of the essential RNase Y. 
Mol Microbiol. 2011 81(6): 1459-1473. 
PubMed:21815947