Difference between revisions of "SftA"

From SubtiWiki
Jump to: navigation, search
Line 22: Line 22:
 
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[murC]]'', ''[[ytpR]]''
 
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[murC]]'', ''[[ytpR]]''
 
|-
 
|-
|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU29805 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU29805 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU29805 Advanced_DNA]
+
|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU29805 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU29805 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU29805 DNA_with_flanks]
 
|-
 
|-
 
|colspan="2" | '''Genetic context''' <br/> [[Image:ytpS_context.gif]]
 
|colspan="2" | '''Genetic context''' <br/> [[Image:ytpS_context.gif]]

Revision as of 11:02, 14 May 2013

  • Description: DNA translocase

Gene name sftA
Synonyms ytpS, cdtA
Essential no
Product DNA translocase
Function resolution of chromosome dimers
Gene expression levels in SubtiExpress: sftA
MW, pI 107 kDa, 5.052
Gene length, protein length 2856 bp, 952 aa
Immediate neighbours murC, ytpR
Sequences Protein DNA DNA_with_flanks
Genetic context
YtpS context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
SftA expression.png
























Categories containing this gene/protein

DNA condensation/ segregation

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU29805

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
    • aids in moving DNA away from the closing septum, binds DNA, DNA-dependent ATPase activity PubMed
    • the two DNA translocases SftA and SpoIIIE synergistically affect chromosome dimer resolution presumably by positioning the dif sites in close proximity, before or after completion of cell division, respectively PubMed
  • Protein family:

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Reviews

Christine Kaimer, Peter L Graumann
Players between the worlds: multifunctional DNA translocases.
Curr Opin Microbiol: 2011, 14(6);719-25
[PubMed:22047950] [WorldCat.org] [DOI] (I p)

Original publications