Difference between revisions of "ComZ"

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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[med]]'', ''[[yjzB]]''
 
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[med]]'', ''[[yjzB]]''
 
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU11310 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU11310 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU11310 Advanced_DNA]
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU11310 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU11310 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU11310 DNA_with_flanks]
 
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|colspan="2" | '''Genetic context''' <br/> [[Image:comZ_context.gif]]
 
|colspan="2" | '''Genetic context''' <br/> [[Image:comZ_context.gif]]

Revision as of 09:54, 14 May 2013

  • Description: late competence gene

Gene name comZ
Synonyms yjzA
Essential no
Product unknown
Function compentence
Gene expression levels in SubtiExpress: comZ
Metabolic function and regulation of this protein in SubtiPathways:
Protein secretion
MW, pI 7 kDa, 4.37
Gene length, protein length 189 bp, 63 aa
Immediate neighbours med, yjzB
Sequences Protein DNA DNA_with_flanks
Genetic context
ComZ context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
ComZ expression.png
























Categories containing this gene/protein

genetic competence

This gene is a member of the following regulons

Spo0A regulon

The gene

Basic information

  • Locus tag: BSU11310

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • repressed under conditions that trigger sporulation (Spo0A) PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Virginie Molle, Masaya Fujita, Shane T Jensen, Patrick Eichenberger, José E González-Pastor, Jun S Liu, Richard Losick
The Spo0A regulon of Bacillus subtilis.
Mol Microbiol: 2003, 50(5);1683-701
[PubMed:14651647] [WorldCat.org] [DOI] (P p)

M Ogura, T Tanaka
Bacillus subtilis comZ (yjzA) negatively affects expression of comG but not comK.
J Bacteriol: 2000, 182(17);4992-4
[PubMed:10940045] [WorldCat.org] [DOI] (P p)

M Ogura, Y Ohshiro, S Hirao, T Tanaka
A new Bacillus subtilis gene, med, encodes a positive regulator of comK.
J Bacteriol: 1997, 179(20);6244-53
[PubMed:9335269] [WorldCat.org] [DOI] (P p)