Difference between revisions of "YfhM"

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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yfhL]]'', ''[[csbB]]''
 
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yfhL]]'', ''[[csbB]]''
 
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU08590 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU08590 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU08590 Advanced_DNA]
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU08590 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU08590 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU08590 DNA_with_flanks]
 
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|colspan="2" | '''Genetic context''' <br/> [[Image:yfhM_context.gif]]
 
|colspan="2" | '''Genetic context''' <br/> [[Image:yfhM_context.gif]]

Revision as of 09:45, 14 May 2013

  • Description: general stress protein, similar to epoxide hydrolase

Gene name yfhM
Synonyms
Essential no
Product unknown
Function survival of ethanol stress
Gene expression levels in SubtiExpress: yfhM
MW, pI 32 kDa, 6.064
Gene length, protein length 858 bp, 286 aa
Immediate neighbours yfhL, csbB
Sequences Protein DNA DNA_with_flanks
Genetic context
YfhM context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
YfhM expression.png
























Categories containing this gene/protein

general stress proteins (controlled by SigB), cell envelope stress proteins (controlled by SigM, V, W, X, Y), poorly characterized/ putative enzymes, sporulation proteins

This gene is a member of the following regulons

SigB regulon, SigW regulon

The gene

Basic information

  • Locus tag: BSU08590

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: AB hydrolase superfamily (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

  • subject to Clp-dependent proteolysis upon glucose starvation PubMed

Expression and regulation

  • Regulatory mechanism:
  • Additional information: subject to Clp-dependent proteolysis upon glucose starvation PubMed

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Dirk Höper, Uwe Völker, Michael Hecker
Comprehensive characterization of the contribution of individual SigB-dependent general stress genes to stress resistance of Bacillus subtilis.
J Bacteriol: 2005, 187(8);2810-26
[PubMed:15805528] [WorldCat.org] [DOI] (P p)

H Antelmann, C Scharf, M Hecker
Phosphate starvation-inducible proteins of Bacillus subtilis: proteomics and transcriptional analysis.
J Bacteriol: 2000, 182(16);4478-90
[PubMed:10913081] [WorldCat.org] [DOI] (P p)

X Huang, A Gaballa, M Cao, J D Helmann
Identification of target promoters for the Bacillus subtilis extracytoplasmic function sigma factor, sigma W.
Mol Microbiol: 1999, 31(1);361-71
[PubMed:9987136] [WorldCat.org] [DOI] (P p)