MhqO

• Description: hydroquinone-specific dioxygenase, confers resistence to methyl-hydroxyquinone
  
  

Gene name	mhqO
Synonyms	ydfO
Essential	no
Product	hydroquinone-specific dioxygenase
Function	resistence to methyl-hydroxyquinone
Gene expression levels in SubtiExpress: mhqO
MW, pI	34 kDa, 4.831
Gene length, protein length	936 bp, 312 aa
Immediate neighbours	mhqN, mhqP
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

general stress proteins (controlled by SigB), resistance against oxidative and electrophile stress

This gene is a member of the following regulons

MhqR regulon, SigB regulon

The gene

Basic information

• Locus tag: BSU05490

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: extradiol ring-cleavage dioxygenase family (according to Swiss-Prot)

• Paralogous protein(s): MhqA, MhqE

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:
  • cytoplasm (according to Swiss-Prot)

Database entries

• Structure: 3OAJ

• UniProt: P96693

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon:
  • mhqN-mhqO-mhqP PubMed
  • mhqO-mhqP PubMed

• Expression browser: mhqO PubMed

• Sigma factor:
  • mhqN: SigA PubMed
  • mhqO: SigB PubMed

• Regulation:
  • induced by catechol and 2-methylhydroquinone (MhqR) PubMed

• Regulatory mechanism:
  • MhqR: transcription repression PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: