Difference between revisions of "UreB"

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|style="background:#ABCDEF;" align="center"|'''Function''' || utilization of urea as alternative nitrogen source
 
|style="background:#ABCDEF;" align="center"|'''Function''' || utilization of urea as alternative nitrogen source
 
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU36650 ureB]
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU36650 ureB]
 
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/UreB UreB]
 
|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/UreB UreB]
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ureC]]'', ''[[ureA]]''
 
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ureC]]'', ''[[ureA]]''
 
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|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB15682&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU36650 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU36650 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU36650 Advanced_DNA]
 
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|colspan="2" | '''Genetic context''' <br/> [[Image:ureB_context.gif]]
 
|colspan="2" | '''Genetic context''' <br/> [[Image:ureB_context.gif]]

Revision as of 14:04, 13 May 2013

  • Description: urease (beta subunit)

Gene name ureB
Synonyms
Essential no
Product urease (beta subunit)
Function utilization of urea as alternative nitrogen source
Gene expression levels in SubtiExpress: ureB
Interactions involving this protein in SubtInteract: UreB
Metabolic function and regulation of this protein in SubtiPathways:
Purine catabolism, Ammonium/ glutamate, Alternative nitrogen sources
MW, pI 13 kDa, 9.751
Gene length, protein length 372 bp, 124 aa
Immediate neighbours ureC, ureA
Sequences Protein DNA Advanced_DNA
Genetic context
UreB context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
UreB expression.png




























Categories containing this gene/protein

utilization of nitrogen sources other than amino acids

This gene is a member of the following regulons

CodY regulon, GlnR regulon, PucR regulon, SigH regulon, TnrA regulon

The gene

Basic information

  • Locus tag: BSU36650

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: Urea + H2O = CO2 + 2 NH3 (according to Swiss-Prot)
  • Protein family: urease beta subunit family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]

Additional information

Expression and regulation

  • Regulation:
    • induced by nitrogen limitation (GlnR, TnrA) PubMed
    • induced in the presence of purine nucleotides (inducer: allantoin) (PucR) PubMed
    • repressed during growth in the presence of branched chain amino acids (CodY) PubMed
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References