Difference between revisions of "CotH"
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|style="background:#ABCDEF;" align="center"|'''Function''' || protection of [[CotU]] and [[CotC]] in the mother cell | |style="background:#ABCDEF;" align="center"|'''Function''' || protection of [[CotU]] and [[CotC]] in the mother cell | ||
|- | |- | ||
| − | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http:// | + | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU36060 cotH] |
|- | |- | ||
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 42 kDa, 5.953 | |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 42 kDa, 5.953 | ||
| Line 22: | Line 22: | ||
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[cotB]]'', ''[[cotG]]'' | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[cotB]]'', ''[[cotG]]'' | ||
|- | |- | ||
| − | | | + | |style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU36060 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU36060 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU36060 Advanced_DNA] |
|- | |- | ||
|colspan="2" | '''Genetic context''' <br/> [[Image:cotH_context.gif]] | |colspan="2" | '''Genetic context''' <br/> [[Image:cotH_context.gif]] | ||
Revision as of 14:02, 13 May 2013
- Description: spore coat protein (inner)
| Gene name | cotH |
| Synonyms | ywrH |
| Essential | no |
| Product | spore coat protein (inner) |
| Function | protection of CotU and CotC in the mother cell |
| Gene expression levels in SubtiExpress: cotH | |
| MW, pI | 42 kDa, 5.953 |
| Gene length, protein length | 1086 bp, 362 aa |
| Immediate neighbours | cotB, cotG |
| Sequences | Protein DNA Advanced_DNA |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU36060
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: cotH family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization:
- spore wall (according to Swiss-Prot)
Database entries
- Structure:
- UniProt: Q45535
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Additional publications: PubMed
Rachele Isticato, Assunta Pelosi, Rita Zilhão, Loredana Baccigalupi, Adriano O Henriques, Maurilio De Felice, Ezio Ricca
CotC-CotU heterodimerization during assembly of the Bacillus subtilis spore coat.
J Bacteriol: 2008, 190(4);1267-75
[PubMed:18065538]
[WorldCat.org]
[DOI]
(I p)
Leif Steil, Mónica Serrano, Adriano O Henriques, Uwe Völker
Genome-wide analysis of temporally regulated and compartment-specific gene expression in sporulating cells of Bacillus subtilis.
Microbiology (Reading): 2005, 151(Pt 2);399-420
[PubMed:15699190]
[WorldCat.org]
[DOI]
(P p)
Loredana Baccigalupi, Gaetano Castaldo, Giuseppina Cangiano, Rachele Isticato, Rosangela Marasco, Maurilio De Felice, Ezio Ricca
GerE-independent expression of cotH leads to CotC accumulation in the mother cell compartment during Bacillus subtilis sporulation.
Microbiology (Reading): 2004, 150(Pt 10);3441-9
[PubMed:15470121]
[WorldCat.org]
[DOI]
(P p)
R Zilhão, G Naclerio, A O Henriques, L Baccigalupi, C P Moran, E Ricca
Assembly requirements and role of CotH during spore coat formation in Bacillus subtilis.
J Bacteriol: 1999, 181(8);2631-3
[PubMed:10198031]
[WorldCat.org]
[DOI]
(P p)
G Naclerio, L Baccigalupi, R Zilhao, M De Felice, E Ricca
Bacillus subtilis spore coat assembly requires cotH gene expression.
J Bacteriol: 1996, 178(15);4375-80
[PubMed:8755863]
[WorldCat.org]
[DOI]
(P p)
