Difference between revisions of "FliS"

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|style="background:#ABCDEF;" align="center"|'''Function''' || [[motility and chemotaxis]]
 
|style="background:#ABCDEF;" align="center"|'''Function''' || [[motility and chemotaxis]]
 
|-
 
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU35330 fliS]
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU35330 fliS]
 
|-
 
|-
 
|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/FliS FliS]
 
|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/FliS FliS]
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[fliT]]'', ''[[fliD]]''
 
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[fliT]]'', ''[[fliD]]''
 
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|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB15550&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU35330 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU35330 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU35330 Advanced_DNA]
 
|-
 
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|colspan="2" | '''Genetic context''' <br/> [[Image:fliS_context.gif]]
 
|colspan="2" | '''Genetic context''' <br/> [[Image:fliS_context.gif]]

Revision as of 13:58, 13 May 2013

  • Description: chaperone for the export of flagellin

Gene name fliS
Synonyms
Essential no
Product chaperone for flagellin export
Function motility and chemotaxis
Gene expression levels in SubtiExpress: fliS
Interactions involving this protein in SubtInteract: FliS
MW, pI 14 kDa, 5.229
Gene length, protein length 399 bp, 133 aa
Immediate neighbours fliT, fliD
Sequences Protein DNA Advanced_DNA
Genetic context
FliS context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
FliS expression.png















Categories containing this gene/protein

motility and chemotaxis

This gene is a member of the following regulons

SigD regulon

The gene

Basic information

  • Locus tag: BSU35330

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: fliS family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Sampriti Mukherjee, Paul Babitzke, Daniel B Kearns
FliW and FliS function independently to control cytoplasmic flagellin levels in Bacillus subtilis.
J Bacteriol: 2013, 195(2);297-306
[PubMed:23144244] [WorldCat.org] [DOI] (I p)

Gert Bange, Nico Kümmerer, Christoph Engel, Gunes Bozkurt, Klemens Wild, Irmgard Sinning
FlhA provides the adaptor for coordinated delivery of late flagella building blocks to the type III secretion system.
Proc Natl Acad Sci U S A: 2010, 107(25);11295-300
[PubMed:20534509] [WorldCat.org] [DOI] (I p)

L Chen, J D Helmann
The Bacillus subtilis sigma D-dependent operon encoding the flagellar proteins FliD, FliS, and FliT.
J Bacteriol: 1994, 176(11);3093-101
[PubMed:8195064] [WorldCat.org] [DOI] (P p)