Difference between revisions of "LacR"
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|style="background:#ABCDEF;" align="center"|'''Function''' || regulation of galactan utilization | |style="background:#ABCDEF;" align="center"|'''Function''' || regulation of galactan utilization | ||
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| − | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http:// | + | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU34170 lacR] |
|- | |- | ||
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 37 kDa, 5.396 | |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 37 kDa, 5.396 | ||
| Line 22: | Line 22: | ||
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[cycB]]'', ''[[lutR]]'' | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[cycB]]'', ''[[lutR]]'' | ||
|- | |- | ||
| − | | | + | |style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU34170 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU34170 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU34170 Advanced_DNA] |
|- | |- | ||
|colspan="2" | '''Genetic context''' <br/> [[Image:lacR_context.gif]] | |colspan="2" | '''Genetic context''' <br/> [[Image:lacR_context.gif]] | ||
Revision as of 13:53, 13 May 2013
- Description: transcriptional repressor of the galactan utilization operon
| Gene name | lacR |
| Synonyms | yvfJ |
| Essential | no |
| Product | transcriptional repressor (LacI family) |
| Function | regulation of galactan utilization |
| Gene expression levels in SubtiExpress: lacR | |
| MW, pI | 37 kDa, 5.396 |
| Gene length, protein length | 990 bp, 330 aa |
| Immediate neighbours | cycB, lutR |
| Sequences | Protein DNA Advanced_DNA |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
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Contents
Categories containing this gene/protein
utilization of specific carbon sources, transcription factors and their control
This gene is a member of the following regulons
The LacR regulon:
The gene
Basic information
- Locus tag: BSU34170
Phenotypes of a mutant
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: LacI family
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- Structure:
- UniProt: O07008
- KEGG entry: [2]
- E.C. number:
Additional information
Expression and regulation
- Operon:
- Sigma factor:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant: GP815 (spc) available in the Stülke lab
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
R A Daniel, J Haiech, F Denizot, J Errington
Isolation and characterization of the lacA gene encoding beta-galactosidase in Bacillus subtilis and a regulator gene, lacR.
J Bacteriol: 1997, 179(17);5636-8
[PubMed:9287030]
[WorldCat.org]
[DOI]
(P p)
J Errington, C H Vogt
Isolation and characterization of mutations in the gene encoding an endogenous Bacillus subtilis beta-galactosidase and its regulator.
J Bacteriol: 1990, 172(1);488-90
[PubMed:2104611]
[WorldCat.org]
[DOI]
(P p)
