Difference between revisions of "SdpI"

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|style="background:#ABCDEF;" align="center"|'''Function''' || protection against [[SdpC]]
 
|style="background:#ABCDEF;" align="center"|'''Function''' || protection against [[SdpC]]
 
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU33780 sdpI]
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU33780 sdpI]
 
|-
 
|-
 
|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/SdpI SdpI]
 
|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/SdpI SdpI]
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[sdpC]]'', ''[[sdpR]]''
 
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[sdpC]]'', ''[[sdpR]]''
 
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|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB15383&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU33780 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU33780 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU33780 Advanced_DNA]
 
|-
 
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|colspan="2" | '''Genetic context''' <br/> [[Image:yvaZ_context.gif]]
 
|colspan="2" | '''Genetic context''' <br/> [[Image:yvaZ_context.gif]]

Revision as of 13:51, 13 May 2013

  • Description: immunity protein, protection against SdpC

Gene name sdpI
Synonyms yvaZ
Essential no
Product immunity protein
Function protection against SdpC
Gene expression levels in SubtiExpress: sdpI
Interactions involving this protein in SubtInteract: SdpI
MW, pI 23 kDa, 9.61
Gene length, protein length 621 bp, 207 aa
Immediate neighbours sdpC, sdpR
Sequences Protein DNA Advanced_DNA
Genetic context
YvaZ context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
SdpI expression.png
























Categories containing this gene/protein

toxins, antitoxins and immunity against toxins, membrane proteins

This gene is a member of the following regulons

AbrB regulon, SdpR regulon

The gene

Basic information

  • Locus tag: BSU33780

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity: in the presence of extracellular SdpC, SdpI binds and sequesters SdpR , this results in induction of the sdpR-sdpI operon PubMed

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Reviews

Original Publications

Tatyana Leonidovna Povolotsky, Ekaterina Orlova, Dorjee G Tamang, Milton H Saier
Defense against cannibalism: the SdpI family of bacterial immunity/signal transduction proteins.
J Membr Biol: 2010, 235(3);145-62
[PubMed:20563570] [WorldCat.org] [DOI] (I p)

Craig D Ellermeier, Errett C Hobbs, Jose E Gonzalez-Pastor, Richard Losick
A three-protein signaling pathway governing immunity to a bacterial cannibalism toxin.
Cell: 2006, 124(3);549-59
[PubMed:16469701] [WorldCat.org] [DOI] (P p)

José E González-Pastor, Errett C Hobbs, Richard Losick
Cannibalism by sporulating bacteria.
Science: 2003, 301(5632);510-3
[PubMed:12817086] [WorldCat.org] [DOI] (I p)