Difference between revisions of "SdpI"
| Line 14: | Line 14: | ||
|style="background:#ABCDEF;" align="center"|'''Function''' || protection against [[SdpC]] | |style="background:#ABCDEF;" align="center"|'''Function''' || protection against [[SdpC]] | ||
|- | |- | ||
| − | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http:// | + | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU33780 sdpI] |
|- | |- | ||
|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/SdpI SdpI] | |colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/SdpI SdpI] | ||
| Line 24: | Line 24: | ||
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[sdpC]]'', ''[[sdpR]]'' | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[sdpC]]'', ''[[sdpR]]'' | ||
|- | |- | ||
| − | | | + | |style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU33780 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU33780 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU33780 Advanced_DNA] |
|- | |- | ||
|colspan="2" | '''Genetic context''' <br/> [[Image:yvaZ_context.gif]] | |colspan="2" | '''Genetic context''' <br/> [[Image:yvaZ_context.gif]] | ||
Revision as of 13:51, 13 May 2013
- Description: immunity protein, protection against SdpC
| Gene name | sdpI |
| Synonyms | yvaZ |
| Essential | no |
| Product | immunity protein |
| Function | protection against SdpC |
| Gene expression levels in SubtiExpress: sdpI | |
| Interactions involving this protein in SubtInteract: SdpI | |
| MW, pI | 23 kDa, 9.61 |
| Gene length, protein length | 621 bp, 207 aa |
| Immediate neighbours | sdpC, sdpR |
| Sequences | Protein DNA Advanced_DNA |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
toxins, antitoxins and immunity against toxins, membrane proteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU33780
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family:
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity: in the presence of extracellular SdpC, SdpI binds and sequesters SdpR , this results in induction of the sdpR-sdpI operon PubMed
- Localization: membrane (according to Swiss-Prot)
Database entries
- Structure:
- UniProt: O32241
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Regulation:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Reviews
José Eduardo González-Pastor
Cannibalism: a social behavior in sporulating Bacillus subtilis.
FEMS Microbiol Rev: 2011, 35(3);415-24
[PubMed:20955377]
[WorldCat.org]
[DOI]
(I p)
Original Publications
Tatyana Leonidovna Povolotsky, Ekaterina Orlova, Dorjee G Tamang, Milton H Saier
Defense against cannibalism: the SdpI family of bacterial immunity/signal transduction proteins.
J Membr Biol: 2010, 235(3);145-62
[PubMed:20563570]
[WorldCat.org]
[DOI]
(I p)
Craig D Ellermeier, Errett C Hobbs, Jose E Gonzalez-Pastor, Richard Losick
A three-protein signaling pathway governing immunity to a bacterial cannibalism toxin.
Cell: 2006, 124(3);549-59
[PubMed:16469701]
[WorldCat.org]
[DOI]
(P p)
José E González-Pastor, Errett C Hobbs, Richard Losick
Cannibalism by sporulating bacteria.
Science: 2003, 301(5632);510-3
[PubMed:12817086]
[WorldCat.org]
[DOI]
(I p)
