Difference between revisions of "ComX"
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|style="background:#ABCDEF;" align="center"|'''Function''' || [[quorum sensing]] | |style="background:#ABCDEF;" align="center"|'''Function''' || [[quorum sensing]] | ||
|- | |- | ||
| − | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http:// | + | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU31700 comX] |
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/ComX ComX] | |colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/ComX ComX] | ||
| Line 24: | Line 24: | ||
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[comP]]'', ''[[comQ]]'' | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[comP]]'', ''[[comQ]]'' | ||
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| − | | | + | |style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU31700 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU31700 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU31700 Advanced_DNA] |
|- | |- | ||
|colspan="2" | '''Genetic context''' <br/> [[Image:comX_context.gif]] | |colspan="2" | '''Genetic context''' <br/> [[Image:comX_context.gif]] | ||
Revision as of 13:44, 13 May 2013
- Description: competence pheromone precursor, transfers cell density signal to ComP; triggers the production of surfactin
| Gene name | comX |
| Synonyms | |
| Essential | no |
| Product | competence pheromone precursor |
| Function | quorum sensing |
| Gene expression levels in SubtiExpress: comX | |
| Interactions involving this protein in SubtInteract: ComX | |
| MW, pI | 6 kDa, 4.358 |
| Gene length, protein length | 165 bp, 55 aa |
| Immediate neighbours | comP, comQ |
| Sequences | Protein DNA Advanced_DNA |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
genetic competence, quorum sensing
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU31700
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification: is synthesized as an inactive precursor, cleaved, and modified (prenylated) by ComQ prior to excretion PubMed
- Cofactor(s):
- Effectors of protein activity:
- Localization:
- secreted (according to Swiss-Prot)
Database entries
- Structure:
- UniProt: P45453
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
The ComX --> surfactin signaling pathway is an example for paracrine signaling in bacteria
References
Reviews
Elizabeth Anne Shank, Roberto Kolter
Extracellular signaling and multicellularity in Bacillus subtilis.
Curr Opin Microbiol: 2011, 14(6);741-7
[PubMed:22024380]
[WorldCat.org]
[DOI]
(I p)
Original publications
Additional publications: PubMed
