Difference between revisions of "ComP"

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|style="background:#ABCDEF;" align="center"|'''Function''' || regulation of [[genetic competence]] and [[quorum sensing]]
 
|style="background:#ABCDEF;" align="center"|'''Function''' || regulation of [[genetic competence]] and [[quorum sensing]]
 
|-
 
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU31690 comP]
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU31690 comP]
 
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/ComP ComP]
 
|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/ComP ComP]
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[comA]]'', ''[[comX]]''
 
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[comA]]'', ''[[comX]]''
 
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|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB15157&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU31690 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU31690 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU31690 Advanced_DNA]
 
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Revision as of 13:44, 13 May 2013

Gene name comP
Synonyms
Essential no
Product two-component sensor kinase
Function regulation of genetic competence and quorum sensing
Gene expression levels in SubtiExpress: comP
Interactions involving this protein in SubtInteract: ComP
MW, pI 89 kDa, 7.997
Gene length, protein length 2307 bp, 769 aa
Immediate neighbours comA, comX
Sequences Protein DNA Advanced_DNA
Genetic context
ComP context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
ComP expression.png


























Categories containing this gene/protein

genetic competence, protein modification, transcription factors and their control, quorum sensing, membrane proteins, phosphoproteins

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU31690

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: autophosphorylation, phosphorylation of ComA
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains: eight transmembrane segments
  • Modification: autophosphorylation on a His residue
  • Cofactor(s):
  • Effectors of protein activity: ComX (extracellular)

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Reviews

Leendert W Hamoen, Gerard Venema, Oscar P Kuipers
Controlling competence in Bacillus subtilis: shared use of regulators.
Microbiology (Reading): 2003, 149(Pt 1);9-17
[PubMed:12576575] [WorldCat.org] [DOI] (P p)

Original Publications