Difference between revisions of "SftA"

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|style="background:#ABCDEF;" align="center"|'''Function''' || resolution of chromosome dimers
 
|style="background:#ABCDEF;" align="center"|'''Function''' || resolution of chromosome dimers
 
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU29805 sftA]
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU29805 sftA]
 
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|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 107 kDa, 5.052   
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 107 kDa, 5.052   
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[murC]]'', ''[[ytpR]]''
 
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[murC]]'', ''[[ytpR]]''
 
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|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB14959&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU29805 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU29805 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU29805 Advanced_DNA]
 
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|colspan="2" | '''Genetic context''' <br/> [[Image:ytpS_context.gif]]
 
|colspan="2" | '''Genetic context''' <br/> [[Image:ytpS_context.gif]]

Revision as of 13:37, 13 May 2013

  • Description: DNA translocase

Gene name sftA
Synonyms ytpS, cdtA
Essential no
Product DNA translocase
Function resolution of chromosome dimers
Gene expression levels in SubtiExpress: sftA
MW, pI 107 kDa, 5.052
Gene length, protein length 2856 bp, 952 aa
Immediate neighbours murC, ytpR
Sequences Protein DNA Advanced_DNA
Genetic context
YtpS context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
SftA expression.png
























Categories containing this gene/protein

DNA condensation/ segregation

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU29805

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
    • aids in moving DNA away from the closing septum, binds DNA, DNA-dependent ATPase activity PubMed
    • the two DNA translocases SftA and SpoIIIE synergistically affect chromosome dimer resolution presumably by positioning the dif sites in close proximity, before or after completion of cell division, respectively PubMed
  • Protein family:

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Reviews

Original publications