Difference between revisions of "YrvM"
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|style="background:#ABCDEF;" align="center"|'''Function''' || tRNA modification | |style="background:#ABCDEF;" align="center"|'''Function''' || tRNA modification | ||
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| − | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http:// | + | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU27540 yrvM] |
|- | |- | ||
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 28 kDa, 8.187 | |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 28 kDa, 8.187 | ||
| Line 22: | Line 22: | ||
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yrvN]]'', ''[[bsrA]]'' | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yrvN]]'', ''[[bsrA]]'' | ||
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| − | | | + | |style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU27540 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU27540 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU27540 Advanced_DNA] |
|- | |- | ||
|colspan="2" | '''Genetic context''' <br/> [[Image:yrvM_context.gif]] | |colspan="2" | '''Genetic context''' <br/> [[Image:yrvM_context.gif]] | ||
Revision as of 13:27, 13 May 2013
- Description: similar to E. coli enzyme that catalyzes ATP-dependent dehydration of N6-threonylcarbamoyladenosine (t6A) to form cyclic N6-threonylcarbamoyladenosine (ct6A)
| Gene name | yrvM |
| Synonyms | |
| Essential | no |
| Product | N6-threonylcarbamoyladenosine cyclase |
| Function | tRNA modification |
| Gene expression levels in SubtiExpress: yrvM | |
| MW, pI | 28 kDa, 8.187 |
| Gene length, protein length | 762 bp, 254 aa |
| Immediate neighbours | yrvN, bsrA |
| Sequences | Protein DNA Advanced_DNA |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU27540
Phenotypes of a mutant
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- catalyzes ATP-dependent dehydration of N6-threonylcarbamoyladenosine (t6A) to form cyclic N6-threonylcarbamoyladenosine (ct6A) (ct6A recognizes the first adenine base of ANN codon at the ribosomal A site) PubMed
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- Structure:
- UniProt: O32037
- KEGG entry: [2]
- E.C. number:
Additional information
Expression and regulation
- Operon:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Kenjyo Miyauchi, Satoshi Kimura, Tsutomu Suzuki
A cyclic form of N6-threonylcarbamoyladenosine as a widely distributed tRNA hypermodification.
Nat Chem Biol: 2013, 9(2);105-11
[PubMed:23242255]
[WorldCat.org]
[DOI]
(I p)
