Difference between revisions of "TrmU"

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|style="background:#ABCDEF;" align="center"|'''Function''' || tRNA modification  
 
|style="background:#ABCDEF;" align="center"|'''Function''' || tRNA modification  
 
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU27500 trmU]
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU27500 trmU]
 
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|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 42 kDa, 4.729   
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 42 kDa, 4.729   
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yrrB]]'', ''[[yrvO]]''
 
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yrrB]]'', ''[[yrvO]]''
 
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|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB14691&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU27500 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU27500 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU27500 Advanced_DNA]
 
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|colspan="2" | '''Genetic context''' <br/> [[Image:trmU_context.gif]]
 
|colspan="2" | '''Genetic context''' <br/> [[Image:trmU_context.gif]]

Revision as of 13:27, 13 May 2013

  • Description: tRNA (5-methylaminomethyl-2-thiouridylate) methyltransferase

Gene name trmU
Synonyms yrrA
Essential yes PubMed
Product tRNA (5-methylaminomethyl-2-thiouridylate) methyltransferase
Function tRNA modification
Gene expression levels in SubtiExpress: trmU
MW, pI 42 kDa, 4.729
Gene length, protein length 1122 bp, 374 aa
Immediate neighbours yrrB, yrvO
Sequences Protein DNA Advanced_DNA
Genetic context
TrmU context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
TrmU expression.png
























Categories containing this gene/protein

translation, essential genes, membrane proteins

This gene is a member of the following regulons

stringent response

The gene

Basic information

  • Locus tag: BSU27500

Phenotypes of a mutant

essential PubMed

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: mnmA/TRMU family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • RelA dependent downregulation (Class I) during stringent response PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References