Difference between revisions of "AdhA"

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|style="background:#ABCDEF;" align="center"|'''Function''' || response to toxic formaldehyde  
 
|style="background:#ABCDEF;" align="center"|'''Function''' || response to toxic formaldehyde  
 
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU27010 adhA]
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU27010 adhA]
 
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|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 37 kDa, 5.367   
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 37 kDa, 5.367   
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yrzP]]'', ''[[yraA]]''
 
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yrzP]]'', ''[[yraA]]''
 
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|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB14643&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU27010 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU27010 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU27010 Advanced_DNA]
 
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Revision as of 13:25, 13 May 2013

  • Description: thiol-dependent aldehyde dehydrogenase, repair of damaged thiol-containing proteins

Gene name adhA
Synonyms
Essential no
Product thiol-dependent aldehyde dehydrogenase,
reduction of aldehydes
Function response to toxic formaldehyde
Gene expression levels in SubtiExpress: adhA
MW, pI 37 kDa, 5.367
Gene length, protein length 1047 bp, 349 aa
Immediate neighbours yrzP, yraA
Sequences Protein DNA Advanced_DNA
Genetic context
AdhA context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
AdhA expression.png



























Categories containing this gene/protein

resistance against oxidative and electrophile stress

This gene is a member of the following regulons

AdhR regulon

The gene

Basic information

  • Locus tag: BSU27010

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Sigma factor:
  • Regulation:
    • induced in the presence of the toxic carbonyls methylglyoxal and formaldehyde (AdhR) PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References