Difference between revisions of "BltD"

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|style="background:#ABCDEF;" align="center"|'''Function''' || spermidine degradation  
 
|style="background:#ABCDEF;" align="center"|'''Function''' || spermidine degradation  
 
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU26600 bltD]
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU26600 bltD]
 
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|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 17 kDa, 6.087   
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 17 kDa, 6.087   
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[blt]]'', ''[[yrkA]]''
 
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[blt]]'', ''[[yrkA]]''
 
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|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB14601&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU26600 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU26600 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU26600 Advanced_DNA]
 
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|colspan="2" | '''Genetic context''' <br/> [[Image:bltD_context.gif]]
 
|colspan="2" | '''Genetic context''' <br/> [[Image:bltD_context.gif]]

Revision as of 13:24, 13 May 2013

  • Description: spermidine/ spermine acetyltransferase

Gene name bltD
Synonyms bmr2D, bmtD
Essential no
Product spermidine/ spermine acetyltransferase
Function spermidine degradation
Gene expression levels in SubtiExpress: bltD
MW, pI 17 kDa, 6.087
Gene length, protein length 456 bp, 152 aa
Immediate neighbours blt, yrkA
Sequences Protein DNA Advanced_DNA
Genetic context
BltD context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
BltD expression.png
























Categories containing this gene/protein

miscellaneous metabolic pathways, membrane proteins

This gene is a member of the following regulons

BltR regulon, Mta regulon

The gene

Basic information

  • Locus tag: BSU26600

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: Acetyl-CoA + an alkane-alpha,omega-diamine = CoA + an N-acetyldiamine (according to Swiss-Prot)
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]

Additional information

Expression and regulation

  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

D P Woolridge, J D Martinez, D E Stringer, E W Gerner
Characterization of a novel spermidine/spermine acetyltransferase, BltD, from Bacillus subtilis.
Biochem J: 1999, 340 ( Pt 3)(Pt 3);753-8
[PubMed:10359661] [WorldCat.org] (P p)

N N Baranova, A Danchin, A A Neyfakh
Mta, a global MerR-type regulator of the Bacillus subtilis multidrug-efflux transporters.
Mol Microbiol: 1999, 31(5);1549-59
[PubMed:10200972] [WorldCat.org] [DOI] (P p)

D P Woolridge, N Vazquez-Laslop, P N Markham, M S Chevalier, E W Gerner, A A Neyfakh
Efflux of the natural polyamine spermidine facilitated by the Bacillus subtilis multidrug transporter Blt.
J Biol Chem: 1997, 272(14);8864-6
[PubMed:9083003] [WorldCat.org] [DOI] (P p)

M Ahmed, L Lyass, P N Markham, S S Taylor, N Vázquez-Laslop, A A Neyfakh
Two highly similar multidrug transporters of Bacillus subtilis whose expression is differentially regulated.
J Bacteriol: 1995, 177(14);3904-10
[PubMed:7608059] [WorldCat.org] [DOI] (P p)