Difference between revisions of "YqeH"

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|style="background:#ABCDEF;" align="center"|'''Function''' || ribosome assembly
 
|style="background:#ABCDEF;" align="center"|'''Function''' || ribosome assembly
 
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU25670 yqeH]
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU25670 yqeH]
 
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|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 40 kDa, 6.009   
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 40 kDa, 6.009   
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[aroD]]'', ''[[yqeG]]''
 
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[aroD]]'', ''[[yqeG]]''
 
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|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB14509&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU25670 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU25670 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU25670 Advanced_DNA]
 
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|colspan="2" | '''Genetic context''' <br/> [[Image:yqeH_context.gif]]
 
|colspan="2" | '''Genetic context''' <br/> [[Image:yqeH_context.gif]]

Revision as of 13:21, 13 May 2013

  • Description: assembly/ stability of the 30S subunit of the ribosome, assembly of the 70S ribosome

Gene name yqeH
Synonyms
Essential yes PubMed
Product GTPase
Function ribosome assembly
Gene expression levels in SubtiExpress: yqeH
MW, pI 40 kDa, 6.009
Gene length, protein length 1098 bp, 366 aa
Immediate neighbours aroD, yqeG
Sequences Protein DNA Advanced_DNA
Genetic context
YqeH context.gif
This image was kindly provided by SubtiList



Categories containing this gene/protein

translation, essential genes, GTP-binding proteins

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU25670

Phenotypes of a mutant

essential PubMed

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: Binds and hydrolyzes GTP and readily exchanges GDP for GTP
  • Protein family: Era/Obg family

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure: 3EC1 (Geobacillus stearothermophilus)
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Naotake Ogasawara, Nara, Japan

Your additional remarks

References

Reviews

Natalie Verstraeten, Maarten Fauvart, Wim Versées, Jan Michiels
The universally conserved prokaryotic GTPases.
Microbiol Mol Biol Rev: 2011, 75(3);507-42, second and third pages of table of contents
[PubMed:21885683] [WorldCat.org] [DOI] (I p)

Robert A Britton
Role of GTPases in bacterial ribosome assembly.
Annu Rev Microbiol: 2009, 63;155-76
[PubMed:19575570] [WorldCat.org] [DOI] (I p)

Original publications

Baskaran Anand, Parag Surana, Balaji Prakash
Deciphering the catalytic machinery in 30S ribosome assembly GTPase YqeH.
PLoS One: 2010, 5(4);e9944
[PubMed:20376346] [WorldCat.org] [DOI] (I e)

Baskaran Anand, Parag Surana, Sagar Bhogaraju, Sushmita Pahari, Balaji Prakash
Circularly permuted GTPase YqeH binds 30S ribosomal subunit: Implications for its role in ribosome assembly.
Biochem Biophys Res Commun: 2009, 386(4);602-6
[PubMed:19540197] [WorldCat.org] [DOI] (I p)

Pek Chin Loh, Takuya Morimoto, Yoshitaka Matsuo, Taku Oshima, Naotake Ogasawara
The GTP-binding protein YqeH participates in biogenesis of the 30S ribosome subunit in Bacillus subtilis.
Genes Genet Syst: 2007, 82(4);281-9
[PubMed:17895579] [WorldCat.org] [DOI] (P p)

William C Uicker, Laura Schaefer, Mark Koenigsknecht, Robert A Britton
The essential GTPase YqeH is required for proper ribosome assembly in Bacillus subtilis.
J Bacteriol: 2007, 189(7);2926-9
[PubMed:17237168] [WorldCat.org] [DOI] (P p)

Takuya Morimoto, Pek Chin Loh, Tomohiro Hirai, Kei Asai, Kazuo Kobayashi, Shigeki Moriya, Naotake Ogasawara
Six GTP-binding proteins of the Era/Obg family are essential for cell growth in Bacillus subtilis.
Microbiology (Reading): 2002, 148(Pt 11);3539-3552
[PubMed:12427945] [WorldCat.org] [DOI] (P p)