Difference between revisions of "YqfL"

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|style="background:#ABCDEF;" align="center"|'''Function''' || inhibits [[CcpN]] activity
 
|style="background:#ABCDEF;" align="center"|'''Function''' || inhibits [[CcpN]] activity
 
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU25240 yqfL]
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU25240 yqfL]
 
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|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 30,4 kDa, 5.78  
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 30,4 kDa, 5.78  
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yqxD]]'', ''[[ccpN]]''
 
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yqxD]]'', ''[[ccpN]]''
 
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|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB14453&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU25240 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU25240 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU25240 Advanced_DNA]
 
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|colspan="2" | '''Genetic context''' <br/> [[Image:yqfL_context.gif]]
 
|colspan="2" | '''Genetic context''' <br/> [[Image:yqfL_context.gif]]

Revision as of 13:19, 13 May 2013

  • Description: Modulator of CcpN activity

Gene name yqfL
Synonyms
Essential no
Product modulator of CcpN activity
Function inhibits CcpN activity
Gene expression levels in SubtiExpress: yqfL
MW, pI 30,4 kDa, 5.78
Gene length, protein length 810 bp, 270 amino acids
Immediate neighbours yqxD, ccpN
Sequences Protein DNA Advanced_DNA
Genetic context
YqfL context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
YqfL expression.png

























Categories containing this gene/protein

carbon core metabolism, transcription factors and their control

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU25240

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry:[2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: negative effector of CcpN activity PubMed
  • Protein family: pyruvate, phosphate dikinase regulatory protein family (according to Swiss-Prot) pyruvate, phosphate dikinase regulatory protein family
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains: nucleotide binding domain (ATP) (151–158)
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure:
  • KEGG entry: [3]

Additional information

Expression and regulation

  • Sigma factor:
  • Regulation: constitutive PubMed
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • Antibody:

Labs working on this gene/protein

Stephane Aymerich, Microbiology and Molecular Genetics, INRA Paris-Grignon, France


Your additional remarks

References

Pascale Servant, Dominique Le Coq, Stéphane Aymerich
CcpN (YqzB), a novel regulator for CcpA-independent catabolite repression of Bacillus subtilis gluconeogenic genes.
Mol Microbiol: 2005, 55(5);1435-51
[PubMed:15720552] [WorldCat.org] [DOI] (P p)