Difference between revisions of "MntR"

From SubtiWiki
Jump to: navigation, search
(Original Publications)
Line 14: Line 14:
 
|style="background:#ABCDEF;" align="center"|'''Function''' || regulation of manganese transport  
 
|style="background:#ABCDEF;" align="center"|'''Function''' || regulation of manganese transport  
 
|-
 
|-
|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU24520 mntR]
+
|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU24520 mntR]
 
|-
 
|-
 
|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/stress_response.html Stress]'''
 
|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/stress_response.html Stress]'''
Line 24: Line 24:
 
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yqhO]]'', ''[[lipM]]''
 
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yqhO]]'', ''[[lipM]]''
 
|-
 
|-
|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB14383&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
+
|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU24520 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU24520 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU24520 Advanced_DNA]
 
|-
 
|-
 
|-
 
|-

Revision as of 13:16, 13 May 2013

  • Description: transcriptional regulator, (repression of mntH and mntA-mntB-mntC-mntD under high Mn(II) conditions)


Gene name mntR
Synonyms yqhN
Essential no
Product transcriptional regulator (DtxR family)
Function regulation of manganese transport
Gene expression levels in SubtiExpress: mntR
Metabolic function and regulation of this protein in SubtiPathways:
Stress
MW, pI 16 kDa, 5.631
Gene length, protein length 426 bp, 142 aa
Immediate neighbours yqhO, lipM
Sequences Protein DNA Advanced_DNA
Genetic context
MntR context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
MntR expression.png




























Categories containing this gene/protein

trace metal homeostasis (Cu, Zn, Ni, Mn, Mo), transcription factors and their control, membrane proteins

This gene is a member of the following regulons

The MntR regulon:

The gene

Basic information

  • Locus tag: BSU24520

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s): Mn(2+) acts as co-repressor (according to PubMed)
  • Effectors of protein activity:

Database entries

  • Structure: 2F5D (complex with manganese), 2HYG (apo-form)
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

John Helmann, Cornell University, USA Homepage

Richard Brennan, Houston, Texas, USA Homepage

Your additional remarks

References

Reviews


Original Publications