Difference between revisions of "SpoIIM"

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|style="background:#ABCDEF;" align="center"|'''Function''' || dissolution of the septal cell wall
 
|style="background:#ABCDEF;" align="center"|'''Function''' || dissolution of the septal cell wall
 
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU23530 spoIIM]
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU23530 spoIIM]
 
|-
 
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/SpoIIM SpoIIM]
 
|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/SpoIIM SpoIIM]
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[fur]]'', ''[[yqkK]]''
 
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[fur]]'', ''[[yqkK]]''
 
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|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB14285&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU23530 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU23530 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU23530 Advanced_DNA]
 
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|colspan="2" | '''Genetic context''' <br/> [[Image:spoIIM_context.gif]]
 
|colspan="2" | '''Genetic context''' <br/> [[Image:spoIIM_context.gif]]

Revision as of 13:13, 13 May 2013

  • Description: required for dissolution of the septal cell wall

Gene name spoIIM
Synonyms
Essential no
Product sporulation protein
Function dissolution of the septal cell wall
Gene expression levels in SubtiExpress: spoIIM
Interactions involving this protein in SubtInteract: SpoIIM
MW, pI 24 kDa, 9.84
Gene length, protein length 642 bp, 214 aa
Immediate neighbours fur, yqkK
Sequences Protein DNA Advanced_DNA
Genetic context
SpoIIM context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
SpoIIM expression.png
























Categories containing this gene/protein

cell wall/ other, sporulation proteins

This gene is a member of the following regulons

SigE regulon

The gene

Basic information

  • Locus tag: BSU23530

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • expressed early during sporulation in the mother cell (SigE) PubMed
    • subject to negative control by YlbO PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Arnaud Chastanet, Richard Losick
Engulfment during sporulation in Bacillus subtilis is governed by a multi-protein complex containing tandemly acting autolysins.
Mol Microbiol: 2007, 64(1);139-52
[PubMed:17376078] [WorldCat.org] [DOI] (P p)

Thierry Doan, Kathleen A Marquis, David Z Rudner
Subcellular localization of a sporulation membrane protein is achieved through a network of interactions along and across the septum.
Mol Microbiol: 2005, 55(6);1767-81
[PubMed:15752199] [WorldCat.org] [DOI] (P p)

Patrick Eichenberger, Masaya Fujita, Shane T Jensen, Erin M Conlon, David Z Rudner, Stephanie T Wang, Caitlin Ferguson, Koki Haga, Tsutomu Sato, Jun S Liu, Richard Losick
The program of gene transcription for a single differentiating cell type during sporulation in Bacillus subtilis.
PLoS Biol: 2004, 2(10);e328
[PubMed:15383836] [WorldCat.org] [DOI] (I p)

P Eichenberger, P Fawcett, R Losick
A three-protein inhibitor of polar septation during sporulation in Bacillus subtilis.
Mol Microbiol: 2001, 42(5);1147-62
[PubMed:11886548] [WorldCat.org] [DOI] (P p)

K Smith, P Youngman
Evidence that the spoIIM gene of Bacillus subtilis is transcribed by RNA polymerase associated with sigma E.
J Bacteriol: 1993, 175(11);3618-27
[PubMed:8501065] [WorldCat.org] [DOI] (P p)