Difference between revisions of "PgsA"
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|style="background:#ABCDEF;" align="center"|'''Function''' || biosynthesis of phospholipids | |style="background:#ABCDEF;" align="center"|'''Function''' || biosynthesis of phospholipids | ||
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| − | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http:// | + | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU16920 pgsA] |
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/fatty_acid_synthesis.html Lipid synthesis]''' | |colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/fatty_acid_synthesis.html Lipid synthesis]''' | ||
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[rodZ]]'', ''[[cinA]]'' | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[rodZ]]'', ''[[cinA]]'' | ||
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| − | | | + | |style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU16920 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU16920 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU16920 Advanced_DNA] |
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Revision as of 12:53, 13 May 2013
- Description: phosphatidylglycerophosphate synthase
| Gene name | pgsA |
| Synonyms | ymfN |
| Essential | yes PubMed |
| Product | phosphatidylglycerophosphate synthase |
| Function | biosynthesis of phospholipids |
| Gene expression levels in SubtiExpress: pgsA | |
| Metabolic function and regulation of this protein in SubtiPathways: Lipid synthesis | |
| MW, pI | 21 kDa, 5.163 |
| Gene length, protein length | 579 bp, 193 aa |
| Immediate neighbours | rodZ, cinA |
| Sequences | Protein DNA Advanced_DNA |
Genetic context 
This image was kindly provided by SubtiList
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Expression at a glance PubMed
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Contents
Categories containing this gene/protein
biosynthesis of lipids, essential genes, membrane proteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU16920
Phenotypes of a mutant
- some point mutations resulting in reduced PgsA activity lead to daptomycin resistance PubMed
essential PubMed
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: CDP-diacylglycerol + sn-glycerol 3-phosphate = CMP + 3(3-sn-phosphatidyl)-sn-glycerol 1-phosphate (according to Swiss-Prot)
- Protein family: CDP-alcohol phosphatidyltransferase class-I family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization: cell membrane at the septum PubMed
Database entries
- Structure:
- UniProt: P46322
- KEGG entry: [2]
- E.C. number: 2.7.8.5
Additional information
Expression and regulation
- Operon:
- Sigma factor:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
