Difference between revisions of "RnjB"
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|style="background:#ABCDEF;" align="center"|'''Function''' || RNA processing and degradation | |style="background:#ABCDEF;" align="center"|'''Function''' || RNA processing and degradation | ||
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| − | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http:// | + | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU16780 rnjB] |
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/RnjB RNase J2] | |colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/RnjB RNase J2] | ||
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[dapA]]'', ''[[tepA]]'' | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[dapA]]'', ''[[tepA]]'' | ||
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| − | | | + | |style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU16780 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU16780 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU16780 Advanced_DNA] |
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Revision as of 12:52, 13 May 2013
- Description: RNase J2
| Gene name | rnjB |
| Synonyms | ymfA |
| Essential | no |
| Product | RNase J2 |
| Function | RNA processing and degradation |
| Gene expression levels in SubtiExpress: rnjB | |
| Interactions involving this protein in SubtInteract: RNase J2 | |
| MW, pI | 56 kDa, 9.18 |
| Gene length, protein length | 1545 bp, 515 aa |
| Immediate neighbours | dapA, tepA |
| Sequences | Protein DNA Advanced_DNA |
Genetic context 
This image was kindly provided by SubtiList
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Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU16780
Phenotypes of a mutant
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: endoribonuclease, involved in processing of thrS mRNA
- Protein family: RNase J subfamily (according to Swiss-Prot)
- Paralogous protein(s): RnjA
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- associated to the RNA degradosome PubMed
- RnjA-RnjB PubMed
- Localization: cytoplasm (according to Swiss-Prot)
Database entries
- KEGG entry: [2]
- E.C. number:
Additional information
Expression and regulation
- Operon:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant: GP45 (spc), GP1113 (miniTn10 spc), both available in Stülke lab
- Expression vector:
- GFP fusion:
- two-hybrid system: B. pertussis adenylate cyclase-based bacterial two hybrid system (BACTH), available in Stülke lab
- Antibody:
Labs working on this gene/protein
Harald Putzer, IBPC Paris, France Homepage
Your additional remarks
References
Reviews
Additional reviews: PubMed
Lehnik-Habrink M, Lewis RJ, Mäder U, Stülke J RNA degradation in Bacillus subtilis: an interplay of essential endo- and exoribonucleases. Mol Microbiol.: 2012, 84(6) 1005-1017. PubMed:22568516
Jamie Richards, Joel G Belasco
Ribonuclease J: how to lead a double life.
Structure: 2011, 19(9);1201-3
[PubMed:21893280]
[WorldCat.org]
[DOI]
(I p)
Ciarán Condon
What is the role of RNase J in mRNA turnover?
RNA Biol: 2010, 7(3);316-21
[PubMed:20458164]
[WorldCat.org]
[DOI]
(I p)
Original publications
Additional publications: PubMed
