Difference between revisions of "RbfA"

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|style="background:#ABCDEF;" align="center"|'''Function''' || translation  
 
|style="background:#ABCDEF;" align="center"|'''Function''' || translation  
 
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU16650 rbfA]
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU16650 rbfA]
 
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|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 13 kDa, 9.338   
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 13 kDa, 9.338   
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ylxP]]'', ''[[truB]]''
 
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ylxP]]'', ''[[truB]]''
 
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|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB13538&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU16650 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU16650 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU16650 Advanced_DNA]
 
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|colspan="2" | '''Genetic context''' <br/> [[Image:rbfA_context.gif]]
 
|colspan="2" | '''Genetic context''' <br/> [[Image:rbfA_context.gif]]

Revision as of 12:52, 13 May 2013

  • Description: ribosome-binding factor A

Gene name rbfA
Synonyms ymxE, ylxO
Essential no
Product ribosome-binding factor A
Function translation
Gene expression levels in SubtiExpress: rbfA
MW, pI 13 kDa, 9.338
Gene length, protein length 351 bp, 117 aa
Immediate neighbours ylxP, truB
Sequences Protein DNA Advanced_DNA
Genetic context
RbfA context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
RbfA expression.png
























Categories containing this gene/protein

translation

This gene is a member of the following regulons

stringent response

The gene

Basic information

  • Locus tag: BSU16650

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: rbfA family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • RelA dependent downregulation (Class I) during stringent response PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Christine Eymann, Georg Homuth, Christian Scharf, Michael Hecker
Bacillus subtilis functional genomics: global characterization of the stringent response by proteome and transcriptome analysis.
J Bacteriol: 2002, 184(9);2500-20
[PubMed:11948165] [WorldCat.org] [DOI] (P p)

K Shazand, J Tucker, M Grunberg-Manago, J C Rabinowitz, T Leighton
Similar organization of the nusA-infB operon in Bacillus subtilis and Escherichia coli.
J Bacteriol: 1993, 175(10);2880-7
[PubMed:8491709] [WorldCat.org] [DOI] (P p)