Difference between revisions of "UxaA"

From SubtiWiki
Jump to: navigation, search
Line 13: Line 13:
 
|style="background:#ABCDEF;" align="center"|'''Function''' || hexuronate utilization  
 
|style="background:#ABCDEF;" align="center"|'''Function''' || hexuronate utilization  
 
|-
 
|-
|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU12390 uxaA]
+
|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU12390 uxaA]
 
|-
 
|-
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 54 kDa, 5.781   
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 54 kDa, 5.781   
Line 21: Line 21:
 
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[uxaB]]'', ''[[yjnA]]''
 
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[uxaB]]'', ''[[yjnA]]''
 
|-
 
|-
|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB13096&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
+
|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU12390 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU12390 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU12390 Advanced_DNA]
 
|-
 
|-
 
|-
 
|-

Revision as of 12:35, 13 May 2013

  • Description: altronate hydrolase

Gene name uxaA
Synonyms yjmJ
Essential no
Product altronate hydrolase
Function hexuronate utilization
Gene expression levels in SubtiExpress: uxaA
MW, pI 54 kDa, 5.781
Gene length, protein length 1491 bp, 497 aa
Immediate neighbours uxaB, yjnA
Sequences Protein DNA Advanced_DNA
Genetic context
UxaA context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
UxaA expression.png


























Categories containing this gene/protein

utilization of specific carbon sources, sporulation proteins

This gene is a member of the following regulons

CcpA regulon, ExuR regulon, SigE regulon

The gene

Basic information

  • Locus tag: BSU12390

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: D-altronate = 2-dehydro-3-deoxy-D-gluconate + H2O (according to Swiss-Prot)
  • Protein family: uxaA family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]

Additional information

Expression and regulation

  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Y Miwa, A Nakata, A Ogiwara, M Yamamoto, Y Fujita
Evaluation and characterization of catabolite-responsive elements (cre) of Bacillus subtilis.
Nucleic Acids Res: 2000, 28(5);1206-10
[PubMed:10666464] [WorldCat.org] [DOI] (I p)

K R Mekjian, E M Bryan, B W Beall, C P Moran
Regulation of hexuronate utilization in Bacillus subtilis.
J Bacteriol: 1999, 181(2);426-33
[PubMed:9882655] [WorldCat.org] [DOI] (P p)

Carlo Rivolta, Blazenka Soldo, Vladimir Lazarevic, Bernard Joris, Catherine Mauël, Dimitri Karamat
A 35.7 kb DNA fragment from the Bacillus subtilis chromosome containing a putative 12.3 kb operon involved in hexuronate catabolism and a perfectly symmetrical hypothetical catabolite-responsive element.
Microbiology (Reading): 1998, 144 ( Pt 4);877-884
[PubMed:9579062] [WorldCat.org] [DOI] (P p)