YjbC

• Description: general stress protein, required for survival of salt stress
  
  

Gene name	yjbC
Synonyms
Essential	no
Product	unknown
Function	unknown
Gene expression levels in SubtiExpress: yjbC
MW, pI	22 kDa, 5.14
Gene length, protein length	576 bp, 192 aa
Immediate neighbours	yjbB, spx
Sequences	Protein DNA Advanced_DNA
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

general stress proteins (controlled by SigB), cell envelope stress proteins (controlled by SigM, V, W, X, Y)

This gene is a member of the following regulons

PerR regulon, SigB regulon, SigM regulon, SigW regulon, SigX regulon

The gene

Basic information

• Locus tag: BSU11490

Phenotypes of a mutant

strongly impaired survival of salt stress PubMed

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure:

• UniProt: O31601

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: yjbC-spx PubMed

• Expression browser: yjbC PubMed

• Sigma factor: SigW, SigB, SigX, PubMed, SigM PubMed

• Regulation:
  • induced by stress (SigB) PubMed
  • transcription is represed by YodB PubMed
  • repressed in the absence of hydrogen peroxide (PerR) PubMed

• Regulatory mechanism: transcription repression
  • PerR: transcription repression PubMed

• Additional information:
  • the mRNA is substantially stabilized upon depletion of RNase Y PubMed

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Lehnik-Habrink M, Schaffer M, Mäder U, Diethmaier C, Herzberg C, Stülke J  
RNA processing in Bacillus subtilis: identification of targets of the essential RNase Y. 
Mol Microbiol. 2011 81(6): 1459-1473. 
PubMed:21815947