Difference between revisions of "MntH"

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|style="background:#ABCDEF;" align="center"|'''Function''' || manganese uptake
 
|style="background:#ABCDEF;" align="center"|'''Function''' || manganese uptake
 
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU04360 mntH]
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU04360 mntH]
 
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/stress_response.html Stress]'''
 
|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/stress_response.html Stress]'''
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ydzK]]'', ''[[ydaS]]''
 
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ydzK]]'', ''[[ydaS]]''
 
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|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB12243&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU04360 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU04360 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU04360 Advanced_DNA]
 
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|colspan="2" | '''Genetic context''' <br/> [[Image:mntH_context.gif]]
 
|colspan="2" | '''Genetic context''' <br/> [[Image:mntH_context.gif]]

Revision as of 12:10, 13 May 2013

  • Description: manganese transporter (proton symport)

Gene name mntH
Synonyms ydaR
Essential no
Product manganese transporter (proton symport))
Function manganese uptake
Gene expression levels in SubtiExpress: mntH
Metabolic function and regulation of this protein in SubtiPathways:
Stress
MW, pI 45 kDa, 9.889
Gene length, protein length 1275 bp, 425 aa
Immediate neighbours ydzK, ydaS
Sequences Protein DNA Advanced_DNA
Genetic context
MntH context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
MntH expression.png




























Categories containing this gene/protein

transporters/ other, trace metal homeostasis (Cu, Zn, Ni, Mn, Mo), membrane proteins

This gene is a member of the following regulons

MntR regulon

The gene

Basic information

  • Locus tag: BSU04360

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: NRAMP family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Sigma factor:
  • Regulation: repressed by Mn(2+) (MntR) PubMed
    • repressed at high Mn(II) concentrations (MntR) PubMed
  • Regulatory mechanism: MntR: transcription repression PubMed
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

John Helmann, Cornell University, USA Homepage

Your additional remarks

References