Difference between revisions of "CwlK"

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|style="background:#ABCDEF;" align="center"|'''Function''' || cell wall turnover
 
|style="background:#ABCDEF;" align="center"|'''Function''' || cell wall turnover
 
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU02810 cwlK]
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU02810 cwlK]
 
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|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 18 kDa, 5.66   
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 18 kDa, 5.66   
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ycdC]]'', ''[[rapJ]]''
 
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ycdC]]'', ''[[rapJ]]''
 
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|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB12075&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU02810 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU02810 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU02810 Advanced_DNA]
 
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|colspan="2" | '''Genetic context''' <br/> [[Image:ycdD_context.gif]]
 
|colspan="2" | '''Genetic context''' <br/> [[Image:ycdD_context.gif]]

Revision as of 12:04, 13 May 2013

  • Description: peptidoglycan hydrolytic L,D-endopeptidase

Gene name cwlK
Synonyms ycdD
Essential no
Product peptidoglycan hydrolytic L,D-endopeptidase
Function cell wall turnover
Gene expression levels in SubtiExpress: cwlK
MW, pI 18 kDa, 5.66
Gene length, protein length 501 bp, 167 aa
Immediate neighbours ycdC, rapJ
Sequences Protein DNA Advanced_DNA
Genetic context
YcdD context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
CwlK expression.png
























Categories containing this gene/protein

cell wall degradation/ turnover, membrane proteins

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU02810

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: peptidase M15C family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Ciaran Condon, IBPC, Paris, France Homepage

Your additional remarks

References

Tatsuya Fukushima, Yang Yao, Toshihiko Kitajima, Hiroki Yamamoto, Junichi Sekiguchi
Characterization of new L,D-endopeptidase gene product CwlK (previous YcdD) that hydrolyzes peptidoglycan in Bacillus subtilis.
Mol Genet Genomics: 2007, 278(4);371-83
[PubMed:17588176] [WorldCat.org] [DOI] (P p)