Difference between revisions of "MinC"
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=== Basic information/ Evolution === | === Basic information/ Evolution === | ||
| − | * '''Catalyzed reaction/ biological activity:''' The Min system prevents minicell formation adjacent to recently completed division sites by promoting the disassembly of the cytokinetic ring, thereby ensuring that cell division occurs only once per cell cycle {{PubMed|20352045}} | + | * '''Catalyzed reaction/ biological activity:''' |
| + | ** The Min system prevents minicell formation adjacent to recently completed division sites by promoting the disassembly of the cytokinetic ring, thereby ensuring that cell division occurs only once per cell cycle {{PubMed|20352045}} | ||
| + | ** binds the C-terminal domain of [[FtsZ]] to inhibit its polymerization {{PubMed|23577149}} | ||
* '''Protein family:''' minC family (according to Swiss-Prot) | * '''Protein family:''' minC family (according to Swiss-Prot) | ||
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* '''[[SubtInteract|Interactions]]:''' | * '''[[SubtInteract|Interactions]]:''' | ||
** ([[MinC]]-[[MinD]])-[[MinJ]]-[[DivIVA]] {{PubMed|20352045}} | ** ([[MinC]]-[[MinD]])-[[MinJ]]-[[DivIVA]] {{PubMed|20352045}} | ||
| + | ** [[FtsZ]] (C-terminal domain)-[[MinC]] {{PubMed|23577149}} | ||
* '''[[Localization]]:''' | * '''[[Localization]]:''' | ||
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* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=minC_2858584_2859264_-1 minC] {{PubMed|22383849}} | * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=minC_2858584_2859264_-1 minC] {{PubMed|22383849}} | ||
| − | * '''Sigma factor:''' | + | * '''[[Sigma factor]]:''' |
** ''[[radC]]'': [[SigM]] {{PubMed|18179421}} | ** ''[[radC]]'': [[SigM]] {{PubMed|18179421}} | ||
** ''[[minC]]'': [[SigH]] {{PubMed|8459776}} | ** ''[[minC]]'': [[SigH]] {{PubMed|8459776}} | ||
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==Original Publications== | ==Original Publications== | ||
'''Additional publications:''' {{PubMed|21926231}} | '''Additional publications:''' {{PubMed|21926231}} | ||
| − | <pubmed>8459776,19019154,1400224,10411726,15317782, 20352045,18588879, 19141479 20566861 20711458 18179421 22457634</pubmed> | + | <pubmed>8459776,19019154,1400224,10411726,15317782, 20352045,18588879, 19141479 20566861 20711458 18179421 22457634 23577149 </pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 12:43, 19 April 2013
- Description: cell-division inhibitor (septum placement), destabilizes FtsZ-rings at new cell poles, part of the Min system (with DivIVA, MinD, MinJ), Noc and the Min system ensure the efficient utilization of the division site at midcell in by ensuring Z ring placement
| Gene name | minC |
| Synonyms | |
| Essential | no |
| Product | cell-division inhibitor |
| Function | septum placement |
| Gene expression levels in SubtiExpress: minC | |
| Interactions involving this protein in SubtInteract: MinC | |
| MW, pI | 24 kDa, 6.262 |
| Gene length, protein length | 678 bp, 226 aa |
| Immediate neighbours | minD, mreD |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
cell division, cell envelope stress proteins (controlled by SigM, V, W, X, Y), membrane proteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU28000
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: minC family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- Structure:
- UniProt: Q01463
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Reviews
Marc Bramkamp, Suey van Baarle
Division site selection in rod-shaped bacteria.
Curr Opin Microbiol: 2009, 12(6);683-8
[PubMed:19884039]
[WorldCat.org]
[DOI]
(I p)
David W Adams, Jeff Errington
Bacterial cell division: assembly, maintenance and disassembly of the Z ring.
Nat Rev Microbiol: 2009, 7(9);642-53
[PubMed:19680248]
[WorldCat.org]
[DOI]
(I p)
Original Publications
Additional publications: PubMed
