Difference between revisions of "SigD regulon"

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(Genes in this regulon)
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= Comments =
 
= Comments =
 
** the [[SigD]] regulon is strongly overexpressed in a ''[[ymdB]]'' mutant (loss of bistable gene expression) {{PubMed|21856853}}
 
** the [[SigD]] regulon is strongly overexpressed in a ''[[ymdB]]'' mutant (loss of bistable gene expression) {{PubMed|21856853}}
 
+
** expression of the [[SigD]] regulon is reduced upon overexpression of [[SlrA]], this can be suppressed by mutations in ''[[remA]]'', ''[[remB]]'', ''[[sinR]]'', or ''[[slrR]]'' {{PubMed|22329926}}
 
= Important publications on the [[SigD]] [[regulon]] =
 
= Important publications on the [[SigD]] [[regulon]] =
 +
<pubmed> 22329926 </pubmed>
 
  <big>''Diethmaier C, Pietack N, Gunka K, Wrede C, Lehnik-Habrink M, Herzberg C, Hübner S, Stülke J''  </big>
 
  <big>''Diethmaier C, Pietack N, Gunka K, Wrede C, Lehnik-Habrink M, Herzberg C, Hübner S, Stülke J''  </big>
 
  <big>'''A Novel Factor Controlling Bistability in ''Bacillus subtilis'': The YmdB Protein Affects</big>
 
  <big>'''A Novel Factor Controlling Bistability in ''Bacillus subtilis'': The YmdB Protein Affects</big>

Revision as of 17:23, 4 January 2013

Regulator

SigD

Genes in this regulon

Comments

    • the SigD regulon is strongly overexpressed in a ymdB mutant (loss of bistable gene expression) PubMed
    • expression of the SigD regulon is reduced upon overexpression of SlrA, this can be suppressed by mutations in remA, remB, sinR, or slrR PubMed

Important publications on the SigD regulon

Loralyn M Cozy, Andrew M Phillips, Rebecca A Calvo, Ashley R Bate, Yi-Huang Hsueh, Richard Bonneau, Patrick Eichenberger, Daniel B Kearns
SlrA/SinR/SlrR inhibits motility gene expression upstream of a hypersensitive and hysteretic switch at the level of σ(D) in Bacillus subtilis.
Mol Microbiol: 2012, 83(6);1210-28
[PubMed:22329926] [WorldCat.org] [DOI] (I p)

Diethmaier C, Pietack N, Gunka K, Wrede C, Lehnik-Habrink M, Herzberg C, Hübner S, Stülke J  
A Novel Factor Controlling Bistability in Bacillus subtilis: The YmdB Protein Affects
Flagellin Expression and Biofilm Formation. 
J Bacteriol.: 2011, 193(21):5997-6007. 
PubMed:21856853


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