PapB

• Description: Xaa-Pro amino-peptidase
  
  

Gene name	papB
Synonyms	ykvY
Essential	no
Product	Xaa-Pro amino-peptidase
Function	degradation of proline-containing peptides
Gene expression levels in SubtiExpress: papB
Metabolic function and regulation of this protein in SubtiPathways: Alternative nitrogen sources
MW, pI	40 kDa, 5.171
Gene length, protein length	1089 bp, 363 aa
Immediate neighbours	zosA, ykvZ
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

utilization of nitrogen sources other than amino acids, coping with hyper-osmotic stress

The gene

Basic information

• Locus tag: BSU13860

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: peptidase M24B family (according to Swiss-Prot)

• Paralogous protein(s): PapA

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure: 3Q6D (B. anthracis Xaa-Pro dipeptidase, 35% identity, 55% similarity)

• UniProt: O31689

• KEGG entry: [2]

• E.C. number: 3.4.11.9

Expression and regulation

• Operon:

• Expression browser: papB PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Adrienne Zaprasis, Jeanette Brill, Marietta Thüring, Guido Wünsche, Magnus Heun, Helena Barzantny, Tamara Hoffmann, Erhard Bremer
Osmoprotection of Bacillus subtilis through import and proteolysis of proline-containing peptides.
Appl Environ Microbiol: 2013, 79(2);576-87
[PubMed:23144141] [WorldCat.org] [DOI] (I p)