Difference between revisions of "RnpB"

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|style="background:#ABCDEF;" align="center"| '''Synonyms''' || ''rnaP ''
 
|style="background:#ABCDEF;" align="center"| '''Synonyms''' || ''rnaP ''
 
|-
 
|-
|style="background:#ABCDEF;" align="center"| '''Essential''' || no
+
|style="background:#ABCDEF;" align="center"| '''Essential''' || yes {{PubMed|23109554}}
 
|-
 
|-
 
|style="background:#ABCDEF;" align="center"| '''Product''' || RNA component of ribonuclease P <br/>([[RNase]] P) (catalytic subunit, ribozyme)
 
|style="background:#ABCDEF;" align="center"| '''Product''' || RNA component of ribonuclease P <br/>([[RNase]] P) (catalytic subunit, ribozyme)
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{{SubtiWiki category|[[Rnases]]}},
 
{{SubtiWiki category|[[Rnases]]}},
 
{{SubtiWiki category|[[translation]]}},
 
{{SubtiWiki category|[[translation]]}},
{{SubtiWiki category|[[ncRNA]]}}
+
{{SubtiWiki category|[[ncRNA]]}},
 +
{{SubtiWiki category|[[essential genes]]}}
  
 
= This gene is a member of the following [[regulons]] =
 
= This gene is a member of the following [[regulons]] =
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===Phenotypes of a mutant ===
 
===Phenotypes of a mutant ===
 
+
* essential {{PubMed|23109554}}
 
=== Database entries ===
 
=== Database entries ===
  
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==Original Publications==
 
==Original Publications==
'''Additional publications:''' {{PubMed|21076397,21622899}}
+
'''Additional publications:''' {{PubMed|23109554,21076397,21622899}}
 
<pubmed>16470227,17355991,11812129,10390342,11454206, 19549719,11454206, 19717440 ,20133747  19932118 20188108 20434461 17299131 14510496 12951523 12836338 11577704 20557101 </pubmed>
 
<pubmed>16470227,17355991,11812129,10390342,11454206, 19549719,11454206, 19717440 ,20133747  19932118 20188108 20434461 17299131 14510496 12951523 12836338 11577704 20557101 </pubmed>
 
[[Category:small RNA]]
 
[[Category:small RNA]]

Revision as of 13:12, 31 October 2012

  • Description: RNA component of RNase P

Gene name rnpB
Synonyms rnaP
Essential yes PubMed
Product RNA component of ribonuclease P
(RNase P) (catalytic subunit, ribozyme)
Function cleavage of precursor sequences
from the 5' ends of pre-tRNAs
Interactions involving this RNA in SubtInteract: RnpB
Gene length 401 bp
Immediate neighbours ypsC, ypsB
Gene sequence (+200bp)
Genetic context
RnpB context.gif
This image was kindly provided by SubtiList








Categories containing this gene/protein

Rnases, translation, ncRNA, essential genes

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag:

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]
  • Structure:
    • 2A64 (from Geobacillus stearothermophilus)
    • 1NBS (specificity domain)
    • 3OKB (complex of RnpA with the RNA RnpB and tRNA, from Thermotoga maritima) PubMed

The RNA

  • Biological activity: 5' end maturation of precursor tRNAs
  • RNA family:
  • cofactor: divalent cations (Ca(II) or Mg (II)) for the stabilization of the complex with pre-tRNA PubMed

Additional information

Expression and regulation

  • Operon:
  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/RNA

Your additional remarks

References

Reviews


Original Publications

Additional publications: PubMed