MutSB

• Description: probable DNA mismatch repair protein
  
  

Gene name	mutSB
Synonyms	yshD
Essential	no
Product	probable DNA mismatch repair protein
Function	DNA repair
Gene expression levels in SubtiExpress: mutSB
MW, pI	87 kDa, 5.79
Gene length, protein length	2355 bp, 785 aa
Immediate neighbours	yshE, polX
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

DNA repair/ recombination, membrane proteins

The gene

Basic information

• Locus tag: BSU28580

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: DNA mismatch repair mutS family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:
  • cell membrane (according to Swiss-Prot)

Database entries

• Structure:

• UniProt: P94545

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon:

• Expression browser: mutSB PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:
  • 1A845 ( mutSB::cat), PubMed, available at BGSC

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

Labs working on this gene/protein

Alessandra Albertini, University of Pavia, Italy homepage

References

P Rossolillo, A M Albertini
Functional analysis of the Bacillus subtilis y shD gene, a mutS paralogue.
Mol Gen Genet: 2001, 264(6);809-18
[PubMed:11254128] [WorldCat.org] [DOI] (P p)