Difference between revisions of "SpsK"

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* '''Description:''' spore coat polysaccharide synthesis <br/><br/>
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* '''Description:''' dTDP -4-dehydrorhamnose reductase, spore coat polysaccharide synthesis <br/><br/>
  
 
{| align="right" border="1" cellpadding="2"  
 
{| align="right" border="1" cellpadding="2"  
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|style="background:#ABCDEF;" align="center"| '''Essential''' || no  
 
|style="background:#ABCDEF;" align="center"| '''Essential''' || no  
 
|-
 
|-
|style="background:#ABCDEF;" align="center"| '''Product''' || unknown
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|style="background:#ABCDEF;" align="center"| '''Product''' || dTDP -4-dehydrorhamnose reductase
 
|-
 
|-
|style="background:#ABCDEF;" align="center"|'''Function''' || spore coat polysaccharide synthesis
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|style="background:#ABCDEF;" align="center"|'''Function''' || rhamnose biosynthesis, spore coat polysaccharide synthesis
 
|-
 
|-
 
|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU37820 spsK]
 
|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU37820 spsK]
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<br/><br/><br/><br/>
 
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= [[Categories]] containing this gene/protein =
 
= [[Categories]] containing this gene/protein =
 +
{{SubtiWiki category|[[miscellaneous metabolic pathways]]}},
 
{{SubtiWiki category|[[sporulation proteins]]}}
 
{{SubtiWiki category|[[sporulation proteins]]}}
  
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* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU37820]
 
* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU37820]
  
* '''E.C. number:'''
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* '''E.C. number:''' [http://www.expasy.org/enzyme/1.1.1.133 1.1.1.133]
  
 
=== Additional information===
 
=== Additional information===
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=References=
 
=References=
<pubmed>9353933 15383836</pubmed>
+
<pubmed>9353933 15383836 22960854 </pubmed>
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 16:10, 18 September 2012

  • Description: dTDP -4-dehydrorhamnose reductase, spore coat polysaccharide synthesis

Gene name spsK
Synonyms ipa-73d
Essential no
Product dTDP -4-dehydrorhamnose reductase
Function rhamnose biosynthesis, spore coat polysaccharide synthesis
Gene expression levels in SubtiExpress: spsK
MW, pI 31 kDa, 6.081
Gene length, protein length 849 bp, 283 aa
Immediate neighbours spsL, spsJ
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
SpsK context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
SpsK expression.png















Categories containing this gene/protein

miscellaneous metabolic pathways, sporulation proteins

This gene is a member of the following regulons

SigE regulon, SigK regulon

The gene

Basic information

  • Locus tag: BSU37820

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: dTDP-4-dehydrorhamnose reductase family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure: 3SC6 (dTDP-4-dehydrorhamnose reductase (rfbD) from Bacillus anthracis str. Ames in complex with NADP; 42% identity, 72% similarity)
  • KEGG entry: [3]

Additional information

Expression and regulation

  • Regulation:
    • expressed late during sporulation in the mother cell (SigK) PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References