Spo0M

• Description: sporulation-control gene
  
  

Gene name	spo0M
Synonyms	ygaI
Essential	no
Product	unknown
Function	sporulation
Gene expression levels in SubtiExpress: spo0M
Interactions involving this protein in SubtInteract: Spo0M
MW, pI	29 kDa, 4.284
Gene length, protein length	774 bp, 258 aa
Immediate neighbours	trnD-Leu2, ygzA
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

sporulation/ other, cell envelope stress proteins (controlled by SigM, V, W, X, Y)

This gene is a member of the following regulons

SigH regulon, SigW regulon

The gene

Basic information

• Locus tag: BSU08760

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: spo0M family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:
  • the protein is degraded by the FtsH metalloprotease PubMed

• Interactions:
  • FtsH-Spo0E PubMed

• Localization:

Database entries

• Structure:

• UniProt: P71088

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: spo0M PubMed

• Expression browser: spo0M PubMed

• Sigma factor: SigH PubMed, SigW PubMed

• Regulation:

• Regulatory mechanism:

• Additional information:
  • the protein is degraded by the FtsH metalloprotease PubMed

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Additional publications: PubMed

Min Cao, Phil A Kobel, Maud M Morshedi, Ming Fang Winston Wu, Chris Paddon, John D Helmann
Defining the Bacillus subtilis sigma(W) regulon: a comparative analysis of promoter consensus search, run-off transcription/macroarray analysis (ROMA), and transcriptional profiling approaches.
J Mol Biol: 2002, 316(3);443-57
[PubMed:11866510] [WorldCat.org] [DOI] (P p)

W D Han, S Kawamoto, Y Hosoya, M Fujita, Y Sadaie, K Suzuki, Y Ohashi, F Kawamura, K Ochi
A novel sporulation-control gene (spo0M) of Bacillus subtilis with a sigmaH-regulated promoter.
Gene: 1998, 217(1-2);31-40
[PubMed:9795118] [WorldCat.org] [DOI] (P p)