Difference between revisions of "SrfAC"

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|style="background:#ABCDEF;" align="center"|'''Function''' || antibiotic synthesis
 
|style="background:#ABCDEF;" align="center"|'''Function''' || antibiotic synthesis
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU03510 srfAC]
 
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|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 143 kDa, 4.97   
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 143 kDa, 4.97   

Revision as of 09:40, 8 August 2012

  • Description: surfactin synthetase / competence

Gene name srfAC
Synonyms comL
Essential no
Product surfactin synthetase / competence
Function antibiotic synthesis
Gene expression levels in SubtiExpress: srfAC
MW, pI 143 kDa, 4.97
Gene length, protein length 3822 bp, 1274 aa
Immediate neighbours comS, srfAD
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
SrfAC context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
SrfAC expression.png


























Categories containing this gene/protein

miscellaneous metabolic pathways, biosynthesis of antibacterial compounds, membrane proteins, phosphoproteins

This gene is a member of the following regulons

Abh regulon, CodY regulon, ComA regulon, PerR regulon, Spx regulon

The gene

Basic information

  • Locus tag: BSU03510

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: acyl carrier domain (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification: phosphorylation on Ser-1003 PubMed
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • repressed during growth in the presence of branched chain amino acids (CodY) PubMed
    • repressed during hydrogen peroxide stress (PerR) PubMed
    • expressed at high cell density (ComA) PubMed
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Reviews

Original publications

Additional publications: PubMed