Difference between revisions of "CapB"

From SubtiWiki
Jump to: navigation, search
Line 13: Line 13:
 
|-
 
|-
 
|style="background:#ABCDEF;" align="center"|'''Function''' || capsule synthesis
 
|style="background:#ABCDEF;" align="center"|'''Function''' || capsule synthesis
 +
|-
 +
|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU35900 capB]
 
|-
 
|-
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 43 kDa, 5.073   
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 43 kDa, 5.073   

Revision as of 16:40, 7 August 2012

  • Description: capsular polyglutamate biosynthesis

Gene name capB
Synonyms ywsC, pgsB
Essential no
Product poly-gamma-glutamate synthetase
Function capsule synthesis
Gene expression levels in SubtiExpress: capB
MW, pI 43 kDa, 5.073
Gene length, protein length 1179 bp, 393 aa
Immediate neighbours capC, rbsR
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YwsC context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
CapB expression.png


























Categories containing this gene/protein

capsule biosynthesis and degradation

This gene is a member of the following regulons

DegU regulon

The gene

Basic information

  • Locus tag: BSU35900

Phenotypes of a mutant

no synthesis of the poly-gamma-glutamate capsule PubMed

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: synthesis of poly-gamma-glutamate from L-Glu PubMed
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
  • Regulatory mechanism: DegU-P: transcription activation PubMed
  • Additional information: The operon is not expressed in the lab strain 168 due to lack of expression of DegQ resulting in inactivity of DegS and DegU PubMed

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Reviews

Original publications

Additional publications: PubMed