Difference between revisions of "IspD"
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| − | + | * '''Description:''' 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase <br/><br/> | |
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|style="background:#ABCDEF;" align="center"|'''Function''' || isoprenoid biosynthesis | |style="background:#ABCDEF;" align="center"|'''Function''' || isoprenoid biosynthesis | ||
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|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 25 kDa, 5.579 | |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 25 kDa, 5.579 | ||
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|colspan="2" | '''Genetic context''' <br/> [[Image:yacM_context.gif]] | |colspan="2" | '''Genetic context''' <br/> [[Image:yacM_context.gif]] | ||
<div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div> | <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div> | ||
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__TOC__ | __TOC__ | ||
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<br/><br/><br/> | <br/><br/><br/> | ||
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* '''Operon:''' ''[[yacL]]-[[ispD]]-[[ispF]]'' {{PubMed|10482513}} | * '''Operon:''' ''[[yacL]]-[[ispD]]-[[ispF]]'' {{PubMed|10482513}} | ||
| − | * | + | * '''[[Sigma factor]]:''' [[SigB]] [http://www.ncbi.nlm.nih.gov/pubmed/15805528 PubMed], [[SigM]] [http://www.ncbi.nlm.nih.gov/sites/entrez/17434969 PubMed] |
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* '''Regulation:''' induced by stress ([[SigB]]) [http://www.ncbi.nlm.nih.gov/pubmed/15805528 PubMed] | * '''Regulation:''' induced by stress ([[SigB]]) [http://www.ncbi.nlm.nih.gov/pubmed/15805528 PubMed] | ||
Revision as of 10:25, 7 August 2012
- Description: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase
| Gene name | ispD |
| Synonyms | yacM |
| Essential | yes PubMed |
| Product | 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase |
| Function | isoprenoid biosynthesis |
| MW, pI | 25 kDa, 5.579 |
| Gene length, protein length | 696 bp, 232 aa |
| Immediate neighbours | yacL, ispF |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
Categories containing this gene/protein
biosynthesis of lipids, general stress proteins (controlled by SigB), cell envelope stress proteins (controlled by SigM, V, W, X, Y), essential genes
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU00900
Phenotypes of a mutant
essential PubMed
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: CTP + 2-C-methyl-D-erythritol 4-phosphate = diphosphate + 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol (according to Swiss-Prot)
- Protein family: ispD family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- Structure:
- UniProt: Q06755
- KEGG entry: [3]
- E.C. number: 2.7.7.60
Additional information
Expression and regulation
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
