Difference between revisions of "MgsR"
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= This gene is a member of the following [[regulons]] = | = This gene is a member of the following [[regulons]] = | ||
| − | {{SubtiWiki regulon|[[SigB regulon]]}} | + | {{SubtiWiki regulon|[[SigB regulon]]}}, |
| + | {{SubtiWiki regulon|[[MgsR regulon]]}} | ||
=The gene= | =The gene= | ||
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=== Additional information=== | === Additional information=== | ||
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=The protein= | =The protein= | ||
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* '''Modification:''' | * '''Modification:''' | ||
| + | ** [[MgsR]] is subject to post-translational redox-sensitive activation by intramolecular disulfide bond formation in response to ethanol stress {{PubMed|22812682}} | ||
* '''Cofactor(s):''' | * '''Cofactor(s):''' | ||
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* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
| − | + | ** MgsR: transcription activation {{PubMed|22812682}} | |
* '''Additional information:''' | * '''Additional information:''' | ||
| + | ** [[MgsR]] is subject to post-translational redox-sensitive activation by intramolecular disulfide bond formation in response to ethanol stress {{PubMed|22812682}} | ||
| + | ** [[MgsR]] is subject to rapid proteolytic degradation by [[ClpX]]-[[ClpP]] and [[ClpC]]-[[ClpP]] {{PubMed|22812682}} | ||
=Biological materials = | =Biological materials = | ||
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=References= | =References= | ||
| − | <pubmed>18643936,,12107147 15805528 18643936, </pubmed> | + | <pubmed>18643936, 22812682,12107147 15805528 18643936, </pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 16:30, 23 July 2012
- Description: transcriptional regulator of a subset of the SigB general stress regulon
| Gene name | mgsR |
| Synonyms | yqgZ |
| Essential | no |
| Product | transcriptional regulator |
| Function | controls a subset of general stress genes |
| Interactions involving this protein in SubtInteract: MgsR | |
| MW, pI | 14 kDa, 9.28 |
| Gene length, protein length | 378 bp, 126 aa |
| Immediate neighbours | trnSL-Gln1, yqgY |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
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Expression at a glance PubMed
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Contents
Categories containing this gene/protein
transcription factors and their control, general stress proteins (controlled by SigB)
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU24770
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: exerts a positive or negative effect on the expression of 53 or 18 stress genes, respectively PubMed
- Protein family: arsC family (according to Swiss-Prot) Arsenate Reductase (ArsC) family, Spx subfamily
- Paralogous protein(s): Spx
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- Structure:
- UniProt: P54503
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Operon: mgsR PubMed
- Regulatory mechanism:
- MgsR: transcription activation PubMed
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
