Difference between revisions of "YuaF"
| Line 43: | Line 43: | ||
= [[Categories]] containing this gene/protein = | = [[Categories]] containing this gene/protein = | ||
{{SubtiWiki category|[[membrane dynamics]]}}, | {{SubtiWiki category|[[membrane dynamics]]}}, | ||
| − | {{SubtiWiki category|[[cell envelope stress proteins (controlled by SigM, V, W, X, Y)]]}} | + | {{SubtiWiki category|[[cell envelope stress proteins (controlled by SigM, V, W, X, Y)]]}}, |
| + | {{SubtiWiki category|[[membrane proteins]]}} | ||
= This gene is a member of the following [[regulons]] = | = This gene is a member of the following [[regulons]] = | ||
| Line 91: | Line 92: | ||
* '''[[SubtInteract|Interactions]]:''' | * '''[[SubtInteract|Interactions]]:''' | ||
| − | ** [[YuaF]]-[[FloT]] | + | ** [[YuaF]]-[[FloT]] {{PubMed|22753055}} |
* '''[[Localization]]:''' | * '''[[Localization]]:''' | ||
| + | ** cell membrane {{PubMed|22753055}} | ||
=== Database entries === | === Database entries === | ||
| Line 141: | Line 143: | ||
=References= | =References= | ||
'''Additional publications:''' {{PubMed|22178969}} | '''Additional publications:''' {{PubMed|22178969}} | ||
| − | <pubmed>18696230,9987136, </pubmed> | + | <pubmed>18696230,9987136, 22753055</pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 17:01, 6 July 2012
- Description: NfeD2, role in maintaining membrane integrity during conditions of cellular stress, confers (together with FloT) resistance to cefuroxime
| Gene name | yuaF |
| Synonyms | |
| Essential | no |
| Product | NfeD family protein NfeD2 |
| Function | involved in the control of membrane fluidity |
| Interactions involving this protein in SubtInteract: YuaF | |
| MW, pI | 18 kDa, 4.042 |
| Gene length, protein length | 522 bp, 174 aa |
| Immediate neighbours | floT, yuaE |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
membrane dynamics, cell envelope stress proteins (controlled by SigM, V, W, X, Y), membrane proteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU31020
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: NfeD family (with YqeZ)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization:
- cell membrane PubMed
Database entries
- Structure: 2K14
- UniProt: O32077
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Additional publications: PubMed
Felix Dempwolff, Heiko M Möller, Peter L Graumann
Synthetic motility and cell shape defects associated with deletions of flotillin/reggie paralogs in Bacillus subtilis and interplay of these proteins with NfeD proteins.
J Bacteriol: 2012, 194(17);4652-61
[PubMed:22753055]
[WorldCat.org]
[DOI]
(I p)
Christina A Walker, Markus Hinderhofer, David J Witte, Winfried Boos, Heiko M Möller
Solution structure of the soluble domain of the NfeD protein YuaF from Bacillus subtilis.
J Biomol NMR: 2008, 42(1);69-76
[PubMed:18696230]
[WorldCat.org]
[DOI]
(P p)
X Huang, A Gaballa, M Cao, J D Helmann
Identification of target promoters for the Bacillus subtilis extracytoplasmic function sigma factor, sigma W.
Mol Microbiol: 1999, 31(1);361-71
[PubMed:9987136]
[WorldCat.org]
[DOI]
(P p)
