Difference between revisions of "RefZ"

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(The protein)
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** TetR-like DNA-binding helix-turn-helix domain at the N-terminus {{PubMed|22730127}}
  
 
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* '''Modification:'''

Revision as of 16:04, 6 July 2012

  • Description: regulator of FtsZ, facilitates switch from medial to polar FtsZ ring placement during sporulation

Gene name yttP
Synonyms
Essential no
Product regulator of FtsZ
Function relocalization of the FtsZ ring
MW, pI 24 kDa, 6.706
Gene length, protein length 621 bp, 207 aa
Immediate neighbours hisJ, ytsP
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YttP context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
YttP expression.png
























Categories containing this gene/protein

cell division, sporulation/ other

This gene is a member of the following regulons

CcpA regulon, PhoP regulon, Spo0A regulon

The gene

Basic information

  • Locus tag: BSU29630

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: facilitates switch from medial to polar FtsZ ring placement during sporulation PubMed
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
    • TetR-like DNA-binding helix-turn-helix domain at the N-terminus PubMed
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Operon: yttP (according to DBTBS)
  • Sigma factor:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Jennifer K Wagner-Herman, Remi Bernard, Roisin Dunne, Alexandre W Bisson-Filho, Krithika Kumar, Trang Nguyen, Lawrence Mulcahy, John Koullias, Frederico J Gueiros-Filho, David Z Rudner
RefZ facilitates the switch from medial to polar division during spore formation in Bacillus subtilis.
J Bacteriol: 2012, 194(17);4608-18
[PubMed:22730127] [WorldCat.org] [DOI] (I p)

Zoltán Prágai, Nicholas E E Allenby, Nicola O'Connor, Sarah Dubrac, Georges Rapoport, Tarek Msadek, Colin R Harwood
Transcriptional regulation of the phoPR operon in Bacillus subtilis.
J Bacteriol: 2004, 186(4);1182-90
[PubMed:14762014] [WorldCat.org] [DOI] (P p)

Virginie Molle, Masaya Fujita, Shane T Jensen, Patrick Eichenberger, José E González-Pastor, Jun S Liu, Richard Losick
The Spo0A regulon of Bacillus subtilis.
Mol Microbiol: 2003, 50(5);1683-701
[PubMed:14651647] [WorldCat.org] [DOI] (P p)

Hans-Matti Blencke, Georg Homuth, Holger Ludwig, Ulrike Mäder, Michael Hecker, Jörg Stülke
Transcriptional profiling of gene expression in response to glucose in Bacillus subtilis: regulation of the central metabolic pathways.
Metab Eng: 2003, 5(2);133-49
[PubMed:12850135] [WorldCat.org] [DOI] (P p)